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    Appbp2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 66884, updated on 23-Jun-2021

    Summary

    Official Symbol
    Appbp2provided by MGI
    Official Full Name
    amyloid beta precursor protein (cytoplasmic tail) binding protein 2provided by MGI
    Primary source
    MGI:MGI:1914134
    See related
    Ensembl:ENSMUSG00000018481
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PA; PAT1; AI465480; 1300003O07Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 24.7), placenta adult (RPKM 21.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Appbp2 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (85082134..85125946, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (85191308..85235120, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (85004810..85048622, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 32 Neighboring gene ribosomal protein L13, pseudogene 1 Neighboring gene RIKEN cDNA 1700125H20 gene Neighboring gene ribosomal protein L13 pseudogene Neighboring gene predicted gene, 23506 Neighboring gene predicted gene, 51947 Neighboring gene predicted gene, 38935 Neighboring gene amyloid beta precursor protein (cytoplasmic tail) binding protein 2, opposite strand Neighboring gene protein phosphatase 1D magnesium-dependent, delta isoform

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin ligase-substrate adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within intracellular transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    amyloid protein-binding protein 2
    Names
    APP-BP2
    amyloid beta precursor protein-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025825.3NP_080101.1  amyloid protein-binding protein 2

      See identical proteins and their annotated locations for NP_080101.1

      Status: PROVISIONAL

      Source sequence(s)
      AL596183
      Consensus CDS
      CCDS25193.1
      UniProtKB/Swiss-Prot
      Q9DAX9
      Related
      ENSMUSP00000018625.10, ENSMUST00000018625.10
      Conserved Domains (1) summary
      pfam13424
      Location:427504
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      85082134..85125946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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