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    Serbp1 serpine1 mRNA binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 66870, updated on 5-Aug-2018

    Summary

    Official Symbol
    Serbp1provided by MGI
    Official Full Name
    serpine1 mRNA binding protein 1provided by MGI
    Primary source
    MGI:MGI:1914120
    See related
    Ensembl:ENSMUSG00000036371 Vega:OTTMUSG00000057415
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pairbp1; AL022786; 1200009K13Rik; 9330147J08Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 69.9), liver E14 (RPKM 49.8) and 25 other tissues See more
    Orthologs

    Genomic context

    See Serbp1 in Genome Data Viewer
    Location:
    6; 6 C1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (67266979..67289302)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (67216973..67239296)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 38825 Neighboring gene Sod1 pseudogene Neighboring gene interleukin 12 receptor, beta 2 Neighboring gene aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    plasminogen activator inhibitor 1 RNA-binding protein
    Names
    PAI-1 mRNA-binding protein
    PAI-RBP1
    PAI1 RNA-binding protein 1
    SERPINE1 mRNA-binding protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113564.1NP_001107036.1  plasminogen activator inhibitor 1 RNA-binding protein isoform 2

      See identical proteins and their annotated locations for NP_001107036.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1.
      Source sequence(s)
      AC130822, AK144764, BY083551
      Consensus CDS
      CCDS85061.1
      UniProtKB/TrEMBL
      Q3UMP4
      Related
      ENSMUSP00000144713.1, OTTMUSP00000073857, ENSMUST00000203436.2, OTTMUST00000141271
      Conserved Domains (2) summary
      pfam04774
      Location:189306
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5119
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal
    2. NM_001113565.1NP_001107037.1  plasminogen activator inhibitor 1 RNA-binding protein isoform 3

      See identical proteins and their annotated locations for NP_001107037.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (23) has an alternate splice site in the CDS, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1.
      Source sequence(s)
      AC130822, AK004678, AK010860
      Consensus CDS
      CCDS85060.1
      UniProtKB/Swiss-Prot
      Q9CY58
      Related
      ENSMUSP00000144913.1, OTTMUSP00000073856, ENSMUST00000203077.2, OTTMUST00000141269
      Conserved Domains (2) summary
      pfam04774
      Location:189297
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5119
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal
    3. NM_001113566.1NP_001107038.1  plasminogen activator inhibitor 1 RNA-binding protein isoform 4

      See identical proteins and their annotated locations for NP_001107038.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has two alternate splice sites in the CDS, as compared to variant 1. The resulting isoform (4) lacks two internal segments, as compared to isoform 1.
      Source sequence(s)
      AC130822, BC030502, BY083551
      Consensus CDS
      CCDS85062.1
      UniProtKB/Swiss-Prot
      Q9CY58
      UniProtKB/TrEMBL
      Q3UEI6
      Related
      ENSMUSP00000145472.1, OTTMUSP00000073838, ENSMUST00000204293.2, OTTMUST00000141238
      Conserved Domains (2) summary
      pfam04774
      Location:189291
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5119
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal
    4. NM_025814.2NP_080090.2  plasminogen activator inhibitor 1 RNA-binding protein isoform 1

      See identical proteins and their annotated locations for NP_080090.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC130822, AK004678
      Consensus CDS
      CCDS20219.1
      UniProtKB/Swiss-Prot
      Q9CY58
      Related
      ENSMUSP00000039110.4, OTTMUSP00000073837, ENSMUST00000042990.6, OTTMUST00000141236
      Conserved Domains (2) summary
      pfam04774
      Location:189312
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
      pfam16174
      Location:5119
      IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      67266979..67289302
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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