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    Mfsd1 major facilitator superfamily domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66868, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mfsd1provided by MGI
    Official Full Name
    major facilitator superfamily domain containing 1provided by MGI
    Primary source
    MGI:MGI:1914118
    See related
    Ensembl:ENSMUSG00000027775
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200003O06Rik
    Expression
    Ubiquitous expression in kidney adult (RPKM 75.5), placenta adult (RPKM 43.9) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mfsd1 in Genome Data Viewer
    Location:
    3; 3 E1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (67490101..67511564)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (67582768..67604231)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (67386690..67408153)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35299 Neighboring gene predicted gene, 25919 Neighboring gene chromatin modifying protein 1A pseudogene Neighboring gene pyrimidinergic receptor P2Y, G-protein coupled, 4 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein localization to lysosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    major facilitator superfamily domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025813.3NP_080089.1  major facilitator superfamily domain-containing protein 1

      See identical proteins and their annotated locations for NP_080089.1

      Status: VALIDATED

      Source sequence(s)
      AC135635
      Consensus CDS
      CCDS38450.1
      UniProtKB/Swiss-Prot
      Q9DC37
      Related
      ENSMUSP00000029344.9, ENSMUST00000029344.10
      Conserved Domains (2) summary
      cd06174
      Location:45438
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:48402
      MFS_1; Major Facilitator Superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      67490101..67511564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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