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    Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing [ Mus musculus (house mouse) ]

    Gene ID: 66830, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nacc1provided by MGI
    Official Full Name
    nucleus accumbens associated 1, BEN and BTB (POZ) domain containingprovided by MGI
    Primary source
    MGI:MGI:1914080
    See related
    Ensembl:ENSMUSG00000001910
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; Nac1; Btbd14b; 2010001H03Rik; 4930511N13Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 78.7), thymus adult (RPKM 50.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Nacc1 in Genome Data Viewer
    Location:
    8 C3; 8 41.02 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (85397106..85414528, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (84670477..84687862, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (87194378..87211761, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39211 Neighboring gene immediate early response 2 Neighboring gene tRNA methyltransferase 1 Neighboring gene lymphoblastomic leukemia 1 Neighboring gene RIKEN cDNA G430095P16 gene Neighboring gene nuclear factor I/X

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nucleus accumbens-associated protein 1
    Names
    BTB (POZ) domain containing 14B
    BTB/POZ domain-containing protein 14B
    NAC-1
    transcriptional repressor NAC1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025788.3NP_080064.3  nucleus accumbens-associated protein 1

      See identical proteins and their annotated locations for NP_080064.3

      Status: VALIDATED

      Source sequence(s)
      BC054800
      Consensus CDS
      CCDS22475.1
      UniProtKB/Swiss-Prot
      Q7TSZ8
      Related
      ENSMUSP00000001975.5, ENSMUST00000001975.6
      Conserved Domains (2) summary
      smart01025
      Location:382460
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      85397106..85414528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531295.5XP_006531358.1  nucleus accumbens-associated protein 1 isoform X2

      Conserved Domains (2) summary
      smart01025
      Location:355433
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)
    2. XM_006531293.5XP_006531356.1  nucleus accumbens-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006531356.1

      UniProtKB/Swiss-Prot
      Q7TSZ8
      Conserved Domains (2) summary
      smart01025
      Location:382460
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)
    3. XM_006531294.5XP_006531357.1  nucleus accumbens-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006531357.1

      UniProtKB/Swiss-Prot
      Q7TSZ8
      Conserved Domains (2) summary
      smart01025
      Location:382460
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)
    4. XM_036154244.1XP_036010137.1  nucleus accumbens-associated protein 1 isoform X2

      Conserved Domains (2) summary
      smart01025
      Location:355433
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)
    5. XM_006531292.4XP_006531355.1  nucleus accumbens-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006531355.1

      UniProtKB/Swiss-Prot
      Q7TSZ8
      Conserved Domains (2) summary
      smart01025
      Location:382460
      BEN; The BEN domain is found in diverse animal proteins
      cd18290
      Location:3125
      BTB_POZ_BTBD14B_NAC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in nucleus accumbens-associated protein 1 (NAC-1)
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