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    Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 66694, updated on 9-Sep-2018

    Summary

    Official Symbol
    Uqcrfs1provided by MGI
    Official Full Name
    ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1provided by MGI
    Primary source
    MGI:MGI:1913944
    See related
    Ensembl:ENSMUSG00000038462 Vega:OTTMUSG00000000670
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI875505; 4430402G14Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 429.8), duodenum adult (RPKM 371.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Uqcrfs1 in Genome Data Viewer
    Location:
    13; 13 A3.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (30540312..30545316, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (30632181..30637185, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene membrane bound O-acyltransferase domain containing 1 Neighboring gene predicted gene, 40863 Neighboring gene angiotensin II receptor, type 1a Neighboring gene RIKEN cDNA 4930519D14 gene Neighboring gene predicted gene, 35109

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on diphenols and related substances as donors IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquinol-cytochrome-c reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane HDA PubMed 
    mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial respiratory chain complex III ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial respiratory chain complex IV ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    respiratory chain IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome b-c1 complex subunit Rieske, mitochondrial
    Names
    RISP
    Rieske protein UQCRFS1
    complex III subunit 5
    cytochrome b-c1 complex subunit 5
    rieske iron-sulfur protein
    ubiquinol-cytochrome c reductase iron-sulfur subunit
    NP_079986.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025710.2NP_079986.1  cytochrome b-c1 complex subunit Rieske, mitochondrial

      See identical proteins and their annotated locations for NP_079986.1

      Status: PROVISIONAL

      Source sequence(s)
      AK014470
      Consensus CDS
      CCDS26416.1
      UniProtKB/Swiss-Prot
      Q9CR68
      Related
      ENSMUSP00000045284.3, OTTMUSP00000000615, ENSMUST00000042834.3, OTTMUST00000001296
      Conserved Domains (3) summary
      cd03470
      Location:151274
      Rieske_cytochrome_bc1; Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including ...
      pfam02921
      Location:80145
      UCR_TM; Ubiquinol cytochrome reductase transmembrane region
      pfam09165
      Location:277
      Ubiq-Cytc-red_N; Ubiquinol-cytochrome c reductase 8 kDa, N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      30540312..30545316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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