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    Tmem186 transmembrane protein 186 [ Mus musculus (house mouse) ]

    Gene ID: 66690, updated on 18-Sep-2024

    Summary

    Official Symbol
    Tmem186provided by MGI
    Official Full Name
    transmembrane protein 186provided by MGI
    Primary source
    MGI:MGI:1913940
    See related
    Ensembl:ENSMUSG00000043140 AllianceGenome:MGI:1913940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810440M13Rik; 4432406C05Rik
    Summary
    Located in mitochondrion. Orthologous to human TMEM186 (transmembrane protein 186). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 9.9), adrenal adult (RPKM 8.7) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmem186 in Genome Data Viewer
    Location:
    16 A1; 16 4.24 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (8451595..8455575, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (8633731..8637711, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene 4-aminobutyrate aminotransferase Neighboring gene zinc finger, MYND domain containing 19 pseudogene Neighboring gene ferritin light chain 2 pseudogene Neighboring gene phosphomannomutase 2 Neighboring gene STARR-positive B cell enhancer ABC_E8616 Neighboring gene calcium regulated heat stable protein 1 Neighboring gene LITAF domain containing Neighboring gene ubiquitin specific peptidase 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:8745912-8746157

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362486.1NP_001349415.1  transmembrane protein 186 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC115005
    2. NM_025708.5NP_079984.2  transmembrane protein 186 isoform 1

      See identical proteins and their annotated locations for NP_079984.2

      Status: VALIDATED

      Source sequence(s)
      AC115005
      Consensus CDS
      CCDS27940.1
      UniProtKB/Swiss-Prot
      Q8BHA7, Q8BHT1, Q9CR76
      UniProtKB/TrEMBL
      Q78HW2
      Related
      ENSMUSP00000053862.9, ENSMUST00000052505.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      8451595..8455575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)