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    Srp72 signal recognition particle 72 [ Mus musculus (house mouse) ]

    Gene ID: 66661, updated on 23-Jun-2021

    Summary

    Official Symbol
    Srp72provided by MGI
    Official Full Name
    signal recognition particle 72provided by MGI
    Primary source
    MGI:MGI:1333795
    See related
    Ensembl:ENSMUSG00000036323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    72kD; 72kDa; C77589; AI132477; BC019196; 5730576P14Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 28.9), limb E14.5 (RPKM 23.3) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Srp72 in Genome Data Viewer
    Location:
    5; 5 C3.3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (77122548..77147782)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (76974701..76999935)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (77403726..77428960)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene phosphoribosyl pyrophosphate amidotransferase Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Neighboring gene predicted gene, 54291 Neighboring gene RIKEN cDNA 1700112J05 gene Neighboring gene ADP-ribosylation factor-like 9 Neighboring gene theg spermatid protein like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 7S RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables 7S RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables TPR domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signal recognition particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of signal recognition particle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of signal recognition particle, endoplasmic reticulum targeting ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    part_of signal recognition particle, endoplasmic reticulum targeting ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    signal recognition particle subunit SRP72
    Names
    signal recognition particle 72 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025691.1NP_079967.1  signal recognition particle subunit SRP72

      See identical proteins and their annotated locations for NP_079967.1

      Status: VALIDATED

      Source sequence(s)
      AK017869, AK133784, BE635216, BY393170, BY647692
      Consensus CDS
      CCDS39119.1
      UniProtKB/TrEMBL
      F8VQC1, Q3UZL8, Q9CS54
      Related
      ENSMUSP00000098648.4, ENSMUST00000101087.10
      Conserved Domains (5) summary
      sd00006
      Location:176204
      TPR; TPR repeat [structural motif]
      sd00004
      Location:341367
      PPR; PPR repeat [structural motif]
      pfam08492
      Location:531584
      SRP72; SRP72 RNA-binding domain
      pfam17004
      Location:36157
      SRP_TPR_like; Putative TPR-like repeat
      cl26002
      Location:24503
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      77122548..77147782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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