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    Nsmce3 NSE3 homolog, SMC5-SMC6 complex component [ Mus musculus (house mouse) ]

    Gene ID: 66647, updated on 26-Sep-2022


    Official Symbol
    Nsmce3provided by MGI
    Official Full Name
    NSE3 homolog, SMC5-SMC6 complex componentprovided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000070520 AllianceGenome:MGI:1913897
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HCA4; Ndnl2; Mageg1; mage-g1; 5730494G16Rik
    Predicted to enable protein dimerization activity. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be located in chromosome, telomeric region and cytoplasm. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; genitourinary system; limb; musculature; and trunk. Orthologous to human NSMCE3 (NSE3 homolog, SMC5-SMC6 complex component). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See Nsmce3 in Genome Data Viewer
    7; 7 C
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64521430..64522788, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64871682..64873040, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 2 Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene predicted gene, 51521 Neighboring gene predicted gene, 32963

    Genomic regions, transcripts, and products


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information



    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    enables protein dimerization activity ISO
    Inferred from Sequence Orthology
    more info
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex ISO
    Inferred from Sequence Orthology
    more info
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info

    General protein information

    Preferred Names
    non-structural maintenance of chromosomes element 3 homolog
    MAGE-G1 antigen
    melanoma antigen, family G, 1
    melanoma-associated antigen G1
    necdin-like 2
    necdin-like protein 2
    non-SMC element 3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023239.5NP_075728.1  non-structural maintenance of chromosomes element 3 homolog

      See identical proteins and their annotated locations for NP_075728.1

      Status: VALIDATED

      Source sequence(s)
      AC135860, AK017727
      Consensus CDS
      Q9CPR8, Q9D378
      ENSMUSP00000091889.3, ENSMUST00000094331.5
      Conserved Domains (1) summary
      MAGE; MAGE family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000073.7 Reference GRCm39 C57BL/6J

      64521430..64522788 complement
      GenBank, FASTA, Sequence Viewer (Graphics)