Format

Send to:

Choose Destination
    • Showing Current items.

    Rpe ribulose-5-phosphate-3-epimerase [ Mus musculus (house mouse) ]

    Gene ID: 66646, updated on 2-Oct-2018

    Summary

    Official Symbol
    Rpeprovided by MGI
    Official Full Name
    ribulose-5-phosphate-3-epimeraseprovided by MGI
    Primary source
    MGI:MGI:1913896
    See related
    Ensembl:ENSMUSG00000026005 Vega:OTTMUSG00000021851
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810429B02Rik; 5730518J08Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 7.6), subcutaneous fat pad adult (RPKM 7.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rpe in Genome Data Viewer
    Location:
    1; 1 C3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (66700812..66719805)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (66747467..66766379)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 2 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene unc-80, NALCN activator Neighboring gene predicted gene, 39655 Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene predicted gene, 46093 Neighboring gene predicted gene, 39656 Neighboring gene heat shock protein 1 (chaperonin) pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carbohydrate binding ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    monosaccharide binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    racemase and epimerase activity, acting on carbohydrates and derivatives IEA
    Inferred from Electronic Annotation
    more info
     
    ribulose-phosphate 3-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribulose-phosphate 3-epimerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    carbohydrate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    cellular carbohydrate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pentose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pentose-phosphate shunt ISO
    Inferred from Sequence Orthology
    more info
     
    pentose-phosphate shunt, non-oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pentose-phosphate shunt, non-oxidative branch ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribulose-phosphate 3-epimerase
    Names
    ribulose-5-phosphate-epimerase
    NP_001297571.1
    NP_001297572.1
    NP_001297573.1
    NP_079959.2
    XP_006496251.1
    XP_006496254.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310642.1NP_001297571.1  ribulose-phosphate 3-epimerase isoform 1

      See identical proteins and their annotated locations for NP_001297571.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK017774, CK619266, DV651671
      Consensus CDS
      CCDS78602.1
      UniProtKB/Swiss-Prot
      Q8VEE0
      UniProtKB/TrEMBL
      B2KGF0
      Related
      ENSMUSP00000109628.1, OTTMUSP00000024471, ENSMUST00000113995.1, OTTMUST00000051849
      Conserved Domains (1) summary
      cd00429
      Location:6221
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...
    2. NM_001310643.1NP_001297572.1  ribulose-phosphate 3-epimerase isoform 3

      See identical proteins and their annotated locations for NP_001297572.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice junction in the 5' end compared to variant 1, which results in translation initiation at a downstream AUG. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AK017774, CF172967, CK619266
      UniProtKB/Swiss-Prot
      Q8VEE0
      Conserved Domains (1) summary
      cd00429
      Location:1146
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...
    3. NM_001310644.1NP_001297573.1  ribulose-phosphate 3-epimerase isoform 4

      See identical proteins and their annotated locations for NP_001297573.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate 5' exon compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AK017774, AK029088, CK619266
      UniProtKB/Swiss-Prot
      Q8VEE0
      Conserved Domains (1) summary
      cd00429
      Location:2174
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...
    4. NM_025683.3NP_079959.2  ribulose-phosphate 3-epimerase isoform 2

      See identical proteins and their annotated locations for NP_079959.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice junction in the 5' end and lacks an alternate 5' exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK017774, CK619266
      Consensus CDS
      CCDS15022.1
      UniProtKB/Swiss-Prot
      Q8VEE0
      Related
      ENSMUSP00000027157.3, OTTMUSP00000024470, ENSMUST00000027157.9, OTTMUST00000051848
      Conserved Domains (1) summary
      cd00429
      Location:6214
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      66700812..66719805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496188.3XP_006496251.1  ribulose-phosphate 3-epimerase isoform X1

      See identical proteins and their annotated locations for XP_006496251.1

      Conserved Domains (1) summary
      cd00429
      Location:6217
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...
    2. XM_006496191.2XP_006496254.1  ribulose-phosphate 3-epimerase isoform X2

      See identical proteins and their annotated locations for XP_006496254.1

      Conserved Domains (1) summary
      cd00429
      Location:1146
      RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187020.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      1108899..1127437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center