Format

Send to:

Choose Destination
    • Showing Current items.

    Diablo diablo, IAP-binding mitochondrial protein [ Mus musculus (house mouse) ]

    Gene ID: 66593, updated on 31-Jan-2019

    Summary

    Official Symbol
    Diabloprovided by MGI
    Official Full Name
    diablo, IAP-binding mitochondrial proteinprovided by MGI
    Primary source
    MGI:MGI:1913843
    See related
    Ensembl:ENSMUSG00000029433
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Smac; AU040403; 0610041G12Rik; 1700006L01Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 115.4), ovary adult (RPKM 33.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Diablo in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (123511330..123524164, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (123961339..123974173, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene interleukin 31 Neighboring gene leucine rich repeat containing 43 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 Neighboring gene microRNA 7647 Neighboring gene VPS33A CORVET/HOPS core subunit Neighboring gene CAP-GLY domain containing linker protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    CD40 receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    mitochondrial intermembrane space TAS
    Traceable Author Statement
    more info
    PubMed 
    mitochondrion HDA PubMed 
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    diablo homolog, mitochondrial
    Names
    direct IAP binding protein with low PI
    direct IAP-binding protein with low pI
    second mitochondria-derived activator of caspase

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023232.3NP_075721.3  diablo homolog, mitochondrial precursor

      See identical proteins and their annotated locations for NP_075721.3

      Status: VALIDATED

      Source sequence(s)
      AK012760, AK133194, BY080746
      Consensus CDS
      CCDS39270.1
      UniProtKB/Swiss-Prot
      Q9JIQ3
      Related
      ENSMUSP00000107214.3, ENSMUST00000111587.9
      Conserved Domains (1) summary
      pfam09057
      Location:19237
      Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      123511330..123524164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center