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    Rpl15 ribosomal protein L15 [ Mus musculus (house mouse) ]

    Gene ID: 66480, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rpl15provided by MGI
    Official Full Name
    ribosomal protein L15provided by MGI
    Primary source
    MGI:MGI:1913730
    See related
    Ensembl:ENSMUSG00000012405 AllianceGenome:MGI:1913730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2510008H07Rik
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cerebellum external granule cell layer; liver; neural retina; olfactory epithelium; and pancreas. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 12. Orthologous to human RPL15 (ribosomal protein L15). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 213.0), CNS E11.5 (RPKM 200.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rpl15 in Genome Data Viewer
    Location:
    14 A1; 14 7.08 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (4198710..4201873)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (18267823..18270986, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2E 1 Neighboring gene predicted gene, 41098 Neighboring gene NFKB inhibitor interacting Ras-like protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:19103554-19103663 Neighboring gene predicted gene 7084 Neighboring gene STARR-seq mESC enhancer starr_36048 Neighboring gene nuclear receptor subfamily 1, group D, member 2 Neighboring gene STARR-seq mESC enhancer starr_36047

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC107261

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in A band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    large ribosomal subunit protein eL15
    Names
    60S ribosomal protein L15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359897.1NP_001346826.1  large ribosomal subunit protein eL15

      Status: VALIDATED

      Source sequence(s)
      AK168807, BU757479, BY169862, CJ093984, CU024892, CX218985
      Consensus CDS
      CCDS36812.1
      UniProtKB/Swiss-Prot
      Q9CWI5, Q9CZM2
      UniProtKB/TrEMBL
      Q3U7D2, Q5M8Q0
      Related
      ENSMUSP00000078388.5, ENSMUST00000079419.12
      Conserved Domains (1) summary
      pfam00827
      Location:2191
      Ribosomal_L15e; Ribosomal L15
    2. NM_001359899.1NP_001346828.1  large ribosomal subunit protein eL15

      Status: VALIDATED

      Source sequence(s)
      AK168807, BU757479, BY169862, CU024892, CX218985
      Consensus CDS
      CCDS36812.1
      UniProtKB/Swiss-Prot
      Q9CWI5, Q9CZM2
      UniProtKB/TrEMBL
      Q3U7D2, Q5M8Q0
      Related
      ENSMUSP00000098362.3, ENSMUST00000100799.9
      Conserved Domains (1) summary
      pfam00827
      Location:2191
      Ribosomal_L15e; Ribosomal L15
    3. NM_025586.3NP_079862.1  large ribosomal subunit protein eL15

      See identical proteins and their annotated locations for NP_079862.1

      Status: VALIDATED

      Source sequence(s)
      AK168807, AW491775, BC087917
      Consensus CDS
      CCDS36812.1
      UniProtKB/Swiss-Prot
      Q9CWI5, Q9CZM2
      UniProtKB/TrEMBL
      Q3U7D2, Q5M8Q0
      Related
      ENSMUSP00000079163.8, ENSMUST00000080281.14
      Conserved Domains (1) summary
      pfam00827
      Location:2191
      Ribosomal_L15e; Ribosomal L15

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      4198710..4201873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)