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    Atp5mk ATP synthase membrane subunit k [ Mus musculus (house mouse) ]

    Gene ID: 66477, updated on 9-Dec-2024

    Summary

    Official Symbol
    Atp5mkprovided by MGI
    Official Full Name
    ATP synthase membrane subunit kprovided by MGI
    Primary source
    MGI:MGI:1891435
    See related
    Ensembl:ENSMUSG00000071528 AllianceGenome:MGI:1891435
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Usmg5; Atp5md; 2010301L15Rik
    Summary
    Located in mitochondrion. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and integumental system. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 6. Orthologous to human ATP5MK (ATP synthase membrane subunit k). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in placenta adult (RPKM 151.0), CNS E18 (RPKM 144.4) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Atp5mk in Genome Data Viewer
    Location:
    19 C3; 19 39.23 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (47071910..47079086, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (47083471..47090647, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene polycomb group ring finger 6 Neighboring gene STARR-positive B cell enhancer ABC_E11037 Neighboring gene STARR-seq mESC enhancer starr_46338 Neighboring gene predicted gene, 23140 Neighboring gene STARR-positive B cell enhancer ABC_E1979 Neighboring gene TATA-box binding protein associated factor 5 Neighboring gene STARR-positive B cell enhancer ABC_E11038 Neighboring gene programmed cell death 11 Neighboring gene STARR-positive B cell enhancer ABC_E11039 Neighboring gene STARR-positive B cell enhancer ABC_E8754 Neighboring gene STARR-seq mESC enhancer starr_46339 Neighboring gene calcium homeostasis modulator family member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    ATP synthase membrane subunit K, mitochondrial
    Names
    ATP synthase membrane subunit DAPIT, mitochondrial
    diabetes-associated protein in insulin-sensitive tissues
    up-regulated during skeletal muscle growth protein 5
    upregulated during skeletal muscle growth 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023211.5NP_075700.2  ATP synthase membrane subunit K, mitochondrial

      See identical proteins and their annotated locations for NP_075700.2

      Status: VALIDATED

      Source sequence(s)
      AC124724
      Consensus CDS
      CCDS38014.1
      UniProtKB/Swiss-Prot
      Q78IK2, Q9ER48
      Related
      ENSMUSP00000093713.4, ENSMUST00000096014.5
      Conserved Domains (1) summary
      pfam14960
      Location:151
      ATP_synth_reg; ATP synthase regulation

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      47071910..47079086 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)