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    Gtf2h5 general transcription factor IIH, polypeptide 5 [ Mus musculus (house mouse) ]

    Gene ID: 66467, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gtf2h5provided by MGI
    Official Full Name
    general transcription factor IIH, polypeptide 5provided by MGI
    Primary source
    MGI:MGI:107227
    See related
    Ensembl:ENSMUSG00000034345
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D17Wsu155e; 2700017P07Rik; 2810432H05Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 27.4), CNS E14 (RPKM 21.4) and 24 other tissues See more
    Orthologs

    Genomic context

    See Gtf2h5 in Genome Data Viewer
    Location:
    17 A1; 17 3.7 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (6079828..6085488)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (6079828..6085488)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene synaptojanin 2 Neighboring gene predicted gene, 46591 Neighboring gene serine active site containing 1 Neighboring gene tubby like protein 4 Neighboring gene predicted gene 5812 Neighboring gene ferritin light chain 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    rDNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to gamma radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide-excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide-excision repair, preincision complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-excision repair, preincision complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphorylation of RNA polymerase II C-terminal domain IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription elongation from RNA polymerase I promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription elongation from RNA polymerase I promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor TFIID complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor TFIIH core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor TFIIH holo complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    general transcription factor IIH subunit 5
    Names
    TFB5 ortholog
    TFIIH basal transcription factor complex TTD-A subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357804.1NP_001344733.1  general transcription factor IIH subunit 5

      Status: VALIDATED

      Source sequence(s)
      AC154650, AK012257, BM940130
      Conserved Domains (1) summary
      pfam06331
      Location:168
      Tfb5; Transcription factor TFIIH complex subunit Tfb5
    2. NM_181392.3NP_852057.2  general transcription factor IIH subunit 5

      See identical proteins and their annotated locations for NP_852057.2

      Status: VALIDATED

      Source sequence(s)
      AK003547, AK013225, BM940130, W50582
      Consensus CDS
      CCDS37423.1
      UniProtKB/Swiss-Prot
      Q8K2X8
      Related
      ENSMUSP00000040355.3, ENSMUST00000039487.9
      Conserved Domains (1) summary
      pfam06331
      Location:168
      Tfb5; Transcription factor TFIIH complex subunit Tfb5

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      6079828..6085488
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523240.3XP_006523303.1  general transcription factor IIH subunit 5 isoform X1

      See identical proteins and their annotated locations for XP_006523303.1

      UniProtKB/Swiss-Prot
      Q8K2X8
      Conserved Domains (1) summary
      pfam06331
      Location:168
      Tfb5; Transcription factor TFIIH complex subunit Tfb5
    2. XM_006523239.3XP_006523302.1  general transcription factor IIH subunit 5 isoform X1

      UniProtKB/Swiss-Prot
      Q8K2X8
      Related
      ENSMUSP00000098515.2, ENSMUST00000100955.2
      Conserved Domains (1) summary
      pfam06331
      Location:168
      Tfb5; Transcription factor TFIIH complex subunit Tfb5
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