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    Magohb mago homolog B, exon junction complex core component [ Mus musculus (house mouse) ]

    Gene ID: 66441, updated on 31-Jan-2019

    Summary

    Official Symbol
    Magohbprovided by MGI
    Official Full Name
    mago homolog B, exon junction complex core componentprovided by MGI
    Primary source
    MGI:MGI:1913691
    See related
    Ensembl:ENSMUSG00000030188
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mago; Magoh; Magoh-rs1; 2010012C16Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 7.8), liver E14 (RPKM 7.0) and 17 other tissues See more
    Orthologs

    Genomic context

    See Magohb in Genome Data Viewer
    Location:
    6 F3; 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (131284389..131293244, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (131234407..131243262, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor, subfamily A, member 2 Neighboring gene predicted gene 5582 Neighboring gene serine/threonine/tyrosine kinase 1 Neighboring gene Y box protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exon-exon junction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exon-exon junction complex ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein mago nashi homolog 2
    Names
    mago nashi protein
    mago-nashi homolog B
    mago-nashi homolog, proliferation-associated, related sequence 1
    protein mago nashi homolog 1-related

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327860.1NP_001314789.1  protein mago nashi homolog 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, resulting in the use of a downstream in-frame translational start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK008200, BE649735
      Consensus CDS
      CCDS85172.1
      UniProtKB/Swiss-Prot
      Q9CQL1
      UniProtKB/TrEMBL
      G3UZW7
      Related
      ENSMUSP00000134663.1, ENSMUST00000173837.5
      Conserved Domains (1) summary
      cl03715
      Location:1102
      Mago_nashi; Mago nashi proteins, integral members of the exon junction complex
    2. NM_025564.2NP_079840.2  protein mago nashi homolog 2 isoform 1

      See identical proteins and their annotated locations for NP_079840.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK008200
      Consensus CDS
      CCDS39670.2
      UniProtKB/Swiss-Prot
      Q9CQL1
      UniProtKB/TrEMBL
      A0A023T778
      Related
      ENSMUSP00000032307.5, ENSMUST00000032307.11
      Conserved Domains (1) summary
      cd11295
      Location:6148
      Mago_nashi; Mago nashi proteins, integral members of the exon junction complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      131284389..131293244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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