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    Asf1a anti-silencing function 1A histone chaperone [ Mus musculus (house mouse) ]

    Gene ID: 66403, updated on 31-Jan-2019

    Summary

    Official Symbol
    Asf1aprovided by MGI
    Official Full Name
    anti-silencing function 1A histone chaperoneprovided by MGI
    Primary source
    MGI:MGI:1913653
    See related
    Ensembl:ENSMUSG00000019857
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C79052; 2310079C17Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 13.4), liver E14 (RPKM 13.2) and 24 other tissues See more
    Orthologs

    Genomic context

    See Asf1a in Genome Data Viewer
    Location:
    10; 10 B3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (53596961..53609225)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (53316767..53329031)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36280 Neighboring gene predicted gene, 20597 Neighboring gene predicted gene, 40650 Neighboring gene minichromosome maintenance 9 homologous recombination repair factor Neighboring gene predicted gene 3902 Neighboring gene family with sequence similarity 184, member A Neighboring gene mannosidase 1, alpha Neighboring gene predicted gene, 16998

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA repair ISO
    Inferred from Sequence Orthology
    more info
     
    DNA replication-dependent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    DNA replication-independent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin assembly or disassembly IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    muscle cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    osteoblast differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone chaperone ASF1A
    Names
    ASF1 anti-silencing function 1 homolog A
    anti-silencing function protein 1 homolog A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025541.3NP_079817.1  histone chaperone ASF1A

      See identical proteins and their annotated locations for NP_079817.1

      Status: VALIDATED

      Source sequence(s)
      AC153949, AK010210
      Consensus CDS
      CCDS23847.1
      UniProtKB/Swiss-Prot
      Q9CQE6
      Related
      ENSMUSP00000020004.6, ENSMUST00000020004.7
      Conserved Domains (1) summary
      pfam04729
      Location:1154
      ASF1_hist_chap; ASF1 like histone chaperone

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      53596961..53609225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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