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    Alkbh7 alkB homolog 7 [ Mus musculus (house mouse) ]

    Gene ID: 66400, updated on 31-Jan-2019

    Summary

    Official Symbol
    Alkbh7provided by MGI
    Official Full Name
    alkB homolog 7provided by MGI
    Primary source
    MGI:MGI:1913650
    See related
    Ensembl:ENSMUSG00000002661
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Abh7; Spata11; 2310045B01Rik; 2510008E23Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 71.0), ovary adult (RPKM 30.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Alkbh7 in Genome Data Viewer
    Location:
    17; 17 D
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (56997339..56999340)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (57136776..57138745)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33509 Neighboring gene caseinolytic mitochondrial matrix peptidase proteolytic subunit Neighboring gene persephin Neighboring gene general transcription factor IIF, polypeptide 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    programmed cell death IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of lipid storage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
    Names
    alkB, alkylation repair homolog 7
    alkylated DNA repair protein alkB homolog 7
    probable alpha-ketoglutarate-dependent dioxygenase ABH7
    spermatogenesis associated 11

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025538.3NP_079814.1  alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial isoform 1 precursor

      See identical proteins and their annotated locations for NP_079814.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC073683, AK009812, AK010930
      Consensus CDS
      CCDS28921.1
      UniProtKB/Swiss-Prot
      Q9D6Z0
      Related
      ENSMUSP00000002737.6, ENSMUST00000002737.6
      Conserved Domains (1) summary
      cl21496
      Location:33200
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
    2. NM_027372.1NP_081648.1  alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial isoform 2

      See identical proteins and their annotated locations for NP_081648.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (2) lacks an internal protein segment compared to isoform 1.
      Source sequence(s)
      AC073683, AK010930
      Consensus CDS
      CCDS57105.1
      UniProtKB/Swiss-Prot
      Q9D6Z0
      Related
      ENSMUSP00000073775.7, ENSMUST00000074141.13
      Conserved Domains (1) summary
      cl21496
      Location:73139
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      56997339..56999340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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