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    Snw1 SNW domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66354, updated on 2-Oct-2018

    Summary

    Official Symbol
    Snw1provided by MGI
    Official Full Name
    SNW domain containing 1provided by MGI
    Primary source
    MGI:MGI:1913604
    See related
    Ensembl:ENSMUSG00000021039
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SKIP; Skiip; NCoA-62; AW048543; 2310008B08Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 29.9), bladder adult (RPKM 19.2) and 23 other tissues See more
    Orthologs

    Genomic context

    See Snw1 in Genome Data Viewer
    Location:
    12; 12 D2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (87449910..87472299, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (88790860..88813249, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene alkB homolog 1, histone H2A dioxygenase Neighboring gene microRNA 3068 Neighboring gene SRA stem-loop interacting RNA binding protein Neighboring gene neural regeneration protein Neighboring gene RNA exonuclease 1 homolog pseudogene Neighboring gene GLE1 RNA export mediator pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC55033

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Notch binding ISO
    Inferred from Sequence Orthology
    more info
     
    SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    androgen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear hormone receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    retinoic acid receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    vitamin D receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to retinoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to retinoic acid ISO
    Inferred from Sequence Orthology
    more info
     
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation by host of viral transcription ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of histone H3-K4 methylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of neurogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of vitamin D receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of retinoic acid receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of vitamin D receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    retinoic acid receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    SMAD protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with cyclin/CDK positive transcription elongation factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SNW domain-containing protein 1
    Names
    SKI interacting protein
    nuclear protein SkiP
    ski-interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025507.2NP_079783.2  SNW domain-containing protein 1

      See identical proteins and their annotated locations for NP_079783.2

      Status: VALIDATED

      Source sequence(s)
      AK009218, AK012384, AK166163
      Consensus CDS
      CCDS49121.1
      UniProtKB/Swiss-Prot
      Q9CSN1
      UniProtKB/TrEMBL
      A0A0B4J1E2, Q3TM37, Q9CV75
      Related
      ENSMUSP00000021428.7, ENSMUST00000021428.8
      Conserved Domains (1) summary
      pfam02731
      Location:178334
      SKIP_SNW; SKIP/SNW domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      87449910..87472299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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