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    Dmac2 distal membrane arm assembly complex 2 [ Mus musculus (house mouse) ]

    Gene ID: 66349, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dmac2provided by MGI
    Official Full Name
    distal membrane arm assembly complex 2provided by MGI
    Primary source
    MGI:MGI:1913599
    See related
    Ensembl:ENSMUSG00000057229
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atp5sl; 2310004L02Rik; C030044E10Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 27.8), kidney adult (RPKM 26.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dmac2 in Genome Data Viewer
    Location:
    7; 7 A3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (25619414..25625550)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (26404512..26410569)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L15 pseudogene Neighboring gene glutamate rich 4 Neighboring gene predicted gene, 38969 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 Neighboring gene branched chain ketoacid dehydrogenase E1, alpha polypeptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial respiratory chain complex I assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with mitochondrial respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with mitochondrial respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    distal membrane-arm assembly complex protein 2
    Names
    ATP synthase subunit s-like protein
    ATP5S-like

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290487.1NP_001277416.1  distal membrane-arm assembly complex protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001277416.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC162614, AK009150
      Consensus CDS
      CCDS71917.1
      UniProtKB/Swiss-Prot
      Q9D7K5
      Related
      ENSMUSP00000076563.5, ENSMUST00000077338.11
      Conserved Domains (2) summary
      cd09293
      Location:149221
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:151176
      LRR_AMN1; leucine-rich repeat [structural motif]
    2. NM_025504.4NP_079780.2  distal membrane-arm assembly complex protein 2 isoform 2

      See identical proteins and their annotated locations for NP_079780.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate first exon compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC162614
      Consensus CDS
      CCDS20988.1
      UniProtKB/TrEMBL
      Q8CA44
      Related
      ENSMUSP00000083115.3, ENSMUST00000085953.4
      Conserved Domains (2) summary
      cd09293
      Location:148220
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:150175
      LRR_AMN1; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      25619414..25625550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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