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    Cenpw centromere protein W [ Mus musculus (house mouse) ]

    Gene ID: 66311, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cenpwprovided by MGI
    Official Full Name
    centromere protein Wprovided by MGI
    Primary source
    MGI:MGI:1913561
    See related
    Ensembl:ENSMUSG00000075266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cug2; 2610036L11Rik
    Expression
    Broad expression in liver E14 (RPKM 9.7), CNS E11.5 (RPKM 8.7) and 20 other tissues See more
    Orthologs
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    Genomic context

    See Cenpw in Genome Data Viewer
    Location:
    10; 10 A4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (30072005..30076599, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (30196009..30200603, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (29915815..29920346, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene aldolase 1 A retrogene 1 pseudogene Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase pseudogene Neighboring gene makorin, ring finger protein, 2 pseudogene Neighboring gene predicted gene, 40622

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in chromosome segregation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in kinetochore assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in kinetochore assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere protein W
    Names
    CENP-W
    cancer-up-regulated gene 2 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109747.1NP_001103217.1  centromere protein W

      See identical proteins and their annotated locations for NP_001103217.1

      Status: VALIDATED

      Source sequence(s)
      AK141272, BF453953, BG804382
      Consensus CDS
      CCDS35876.1
      UniProtKB/Swiss-Prot
      Q3URR0
      UniProtKB/TrEMBL
      B2RVH1
      Related
      ENSMUSP00000097565.5, ENSMUST00000099985.6
      Conserved Domains (1) summary
      pfam15510
      Location:186
      CENP-W; Centromere kinetochore component W

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      30072005..30076599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512814.4XP_006512877.1  centromere protein W isoform X1

      Conserved Domains (1) summary
      pfam15510
      Location:140
      CENP-W; CENP-W protein
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