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    Cenpw centromere protein W [ Mus musculus (house mouse) ]

    Gene ID: 66311, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cenpwprovided by MGI
    Official Full Name
    centromere protein Wprovided by MGI
    Primary source
    MGI:MGI:1913561
    See related
    Ensembl:ENSMUSG00000075266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cug2; 2610036L11Rik
    Expression
    Broad expression in liver E14 (RPKM 9.7), CNS E11.5 (RPKM 8.7) and 20 other tissues See more
    Orthologs

    Genomic context

    See Cenpw in Genome Data Viewer
    Location:
    10; 10 A4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (30196009..30200604, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (29915815..29920346, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene aldolase 1 A retrogene 1 pseudogene Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase pseudogene Neighboring gene makorin, ring finger protein, 2 pseudogene Neighboring gene predicted gene, 40622

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromosome segregation ISO
    Inferred from Sequence Orthology
    more info
     
    kinetochore assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    kinetochore assembly ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere protein W
    Names
    CENP-W
    cancer-up-regulated gene 2 protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109747.1NP_001103217.1  centromere protein W

      See identical proteins and their annotated locations for NP_001103217.1

      Status: VALIDATED

      Source sequence(s)
      AK141272, BF453953, BG804382
      Consensus CDS
      CCDS35876.1
      UniProtKB/Swiss-Prot
      Q3URR0
      UniProtKB/TrEMBL
      B2RVH1
      Related
      ENSMUSP00000097565.4, ENSMUST00000099985.5
      Conserved Domains (1) summary
      pfam15510
      Location:186
      CENP-W; Centromere kinetochore component W

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      30196009..30200604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512814.3XP_006512877.1  centromere protein W isoform X1

      Conserved Domains (1) summary
      pfam15510
      Location:140
      CENP-W; Centromere kinetochore component W
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