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    Pigyl phosphatidylinositol glycan anchor biosynthesis, class Y-like [ Mus musculus (house mouse) ]

    Gene ID: 66268, updated on 23-May-2018

    Summary

    Official Symbol
    Pigylprovided by MGI
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis, class Y-likeprovided by MGI
    Primary source
    MGI:MGI:1913518
    See related
    Ensembl:ENSMUSG00000010607 Vega:OTTMUSG00000034073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pigy; PIG-Y; 1810008A14Rik
    Summary
    This gene encodes a homolog of a human protein that functions in glycosylphosphatidylinositol biosynthesis. The human protein is expressed from an unusual locus that encodes two distinct proteins in upstream and downstream CDSes; however, in mouse these two proteins are expressed from distinct loci. The product of this locus is highly similar to the protein expressed from the human downstream CDS. A separate mouse locus on chromosome 6 is orthologous to the human locus and encodes a protein similar to the human protein expressed from the upstream CDS. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 30.9), ovary adult (RPKM 27.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pigyl in Genome Data Viewer
    Location:
    9; 9 A3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (22156846..22158355)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21961290..21962799)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene acid phosphatase 5, tartrate resistant Neighboring gene predicted gene, 39306 Neighboring gene zinc finger protein 867 pseudogene Neighboring gene ribosomal protein L15, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to phosphatidylinositol N-acetylglucosaminyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
    Names
    phosphatidylinositol-glycan biosynthesis class Y protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082532.1NP_001076001.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit Y precursor

      See identical proteins and their annotated locations for NP_001076001.1

      Status: REVIEWED

      Source sequence(s)
      AI414555, AK007367, BU558514
      Consensus CDS
      CCDS52742.1
      UniProtKB/Swiss-Prot
      P0C1P0
      UniProtKB/TrEMBL
      Q9CQH2
      Related
      ENSMUSP00000116929.1, OTTMUSP00000046559, ENSMUST00000123680.1, OTTMUST00000086092
      Conserved Domains (1) summary
      pfam15159
      Location:570
      PIG-Y; Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      22156846..22158355
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_025457.1: Suppressed sequence

      Description
      NM_025457.1: This RefSeq was permanently suppressed because currently there is limited support for the transcript but not the protein.
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