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    Ssr2 signal sequence receptor, beta [ Mus musculus (house mouse) ]

    Gene ID: 66256, updated on 26-Sep-2022

    Summary

    Official Symbol
    Ssr2provided by MGI
    Official Full Name
    signal sequence receptor, betaprovided by MGI
    Primary source
    MGI:MGI:1913506
    See related
    Ensembl:ENSMUSG00000041355 AllianceGenome:MGI:1913506
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TLAP; TRAPB; SSR-beta; TRAPbeta; 1500032E05Rik
    Summary
    Acts upstream of or within in utero embryonic development. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in cranium; genitourinary system; and pancreas epithelium. Orthologous to human SSR2 (signal sequence receptor subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 192.7), large intestine adult (RPKM 147.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ssr2 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (88486915..88495727)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (88579608..88588420)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ubiquilin 4 Neighboring gene RNA transcription, translation and transport factor, pseudogene Neighboring gene predicted gene, 52660 Neighboring gene rho/rac guanine nucleotide exchange factor (GEF) 2 Neighboring gene predicted gene, 40090

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    translocon-associated protein subunit beta
    Names
    signal sequence receptor subunit beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356316.1NP_001343245.1  translocon-associated protein subunit beta isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC145168
      Consensus CDS
      CCDS89648.1
      UniProtKB/TrEMBL
      A0A0A6YXB7
      Related
      ENSMUSP00000141922.2, ENSMUST00000192495.6
      Conserved Domains (1) summary
      pfam05753
      Location:15181
      TRAP_beta; Translocon-associated protein beta (TRAPB)
    2. NM_001356317.1NP_001343246.1  translocon-associated protein subunit beta isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC145168, AK005340
      Consensus CDS
      CCDS17480.1
      UniProtKB/Swiss-Prot
      Q9CX54
      UniProtKB/TrEMBL
      A0A6P5P9C5, A0A8C6N4A2
      Related
      ENSMUSP00000141441.2, ENSMUST00000195014.6
      Conserved Domains (1) summary
      pfam05753
      Location:15179
      TRAP_beta; Translocon-associated protein beta (TRAPB)
    3. NM_001356318.1NP_001343247.1  translocon-associated protein subunit beta isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC145168
      Conserved Domains (1) summary
      pfam05753
      Location:15177
      TRAP_beta; Translocon-associated protein beta (TRAPB)
    4. NM_001356319.1NP_001343248.1  translocon-associated protein subunit beta isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC145168
      Consensus CDS
      CCDS89649.1
      UniProtKB/TrEMBL
      A0A0A6YVZ1
      Related
      ENSMUSP00000141325.2, ENSMUST00000193934.6
      Conserved Domains (1) summary
      pfam05753
      Location:15160
      TRAP_beta; Translocon-associated protein beta (TRAPB)
    5. NM_025448.4NP_079724.1  translocon-associated protein subunit beta isoform 2 precursor

      See identical proteins and their annotated locations for NP_079724.1

      Status: VALIDATED

      Source sequence(s)
      AC145168, AK050505
      Consensus CDS
      CCDS17480.1
      UniProtKB/Swiss-Prot
      Q9CPW5, Q9CX54
      UniProtKB/TrEMBL
      A0A6P5P9C5, A0A8C6N4A2
      Related
      ENSMUSP00000045456.8, ENSMUST00000035785.9
      Conserved Domains (1) summary
      pfam05753
      Location:15179
      TRAP_beta; Translocon-associated protein beta (TRAPB)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      88486915..88495727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)