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    Sec61b Sec61 beta subunit [ Mus musculus (house mouse) ]

    Gene ID: 66212, updated on 9-Sep-2018

    Summary

    Official Symbol
    Sec61bprovided by MGI
    Official Full Name
    Sec61 beta subunitprovided by MGI
    Primary source
    MGI:MGI:1913462
    See related
    Ensembl:ENSMUSG00000053317 Vega:OTTMUSG00000006799
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI326121; AW122942; 1190006C12Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 203.0), colon adult (RPKM 171.1) and 27 other tissues See more
    Orthologs

    Genomic context

    See Sec61b in Genome Data Viewer
    Location:
    4; 4 B1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (47474661..47483233)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (47487533..47496105)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene microfibrillar-associated protein 1B pseudogene Neighboring gene asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) Neighboring gene predicted gene, 42283 Neighboring gene predicted gene, 42284 Neighboring gene predicted gene, 32487

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102034

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ARF guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to P-P-bond-hydrolysis-driven protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    epidermal growth factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    SRP-dependent cotranslational protein targeting to membrane, translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    posttranslational protein targeting to membrane, translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein import into nucleus, translocation ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    retrograde protein transport, ER to cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Sec61 translocon complex IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum Sec complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum quality control compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    protein transport protein Sec61 subunit beta

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024171.2NP_077133.1  protein transport protein Sec61 subunit beta

      See identical proteins and their annotated locations for NP_077133.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004505
      Consensus CDS
      CCDS38759.1
      UniProtKB/Swiss-Prot
      Q9CQS8
      Related
      ENSMUSP00000067681.5, OTTMUSP00000007204, ENSMUST00000065678.5, OTTMUST00000015669
      Conserved Domains (1) summary
      pfam03911
      Location:5390
      Sec61_beta; Sec61beta family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      47474661..47483233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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