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    Vta1 vesicle (multivesicular body) trafficking 1 [ Mus musculus (house mouse) ]

    Gene ID: 66201, updated on 23-Jun-2021

    Summary

    Official Symbol
    Vta1provided by MGI
    Official Full Name
    vesicle (multivesicular body) trafficking 1provided by MGI
    Primary source
    MGI:MGI:1913451
    See related
    Ensembl:ENSMUSG00000019868
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LIP5; SBP1; C85340; AU040813; 1110001D18Rik; 1110059P08Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 23.2), whole brain E14.5 (RPKM 22.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Vta1 in Genome Data Viewer
    Location:
    10; 10 A2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (14530504..14581334, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (14654760..14705542, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (14375139..14425295, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor G6 Neighboring gene VISTA enhancer mm116 Neighboring gene ribosomal protein L23A pseudogene Neighboring gene RIKEN cDNA 1700016L04 gene Neighboring gene gap junction protein, epsilon 1 Neighboring gene heat shock protein 8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in multivesicular body sorting pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in viral budding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in multivesicular body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vacuolar protein sorting-associated protein VTA1 homolog
    Names
    SKD1-binding protein 1
    Vps20-associated 1 homolog
    lysosomal trafficking regulator interacting protein-5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025418.3NP_079694.2  vacuolar protein sorting-associated protein VTA1 homolog

      See identical proteins and their annotated locations for NP_079694.2

      Status: VALIDATED

      Source sequence(s)
      AK002611, BP770041, CX212626
      Consensus CDS
      CCDS23705.1
      UniProtKB/Swiss-Prot
      Q9CR26
      Related
      ENSMUSP00000119829.2, ENSMUST00000154132.8
      Conserved Domains (2) summary
      pfam04652
      Location:22152
      Vta1; Vta1 like
      cl28408
      Location:183264
      UBQ; Ubiquitin homologues

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      14530504..14581334 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512809.5XP_006512872.1  vacuolar protein sorting-associated protein VTA1 homolog isoform X1

      See identical proteins and their annotated locations for XP_006512872.1

      Related
      ENSMUSP00000118498.2, ENSMUST00000149485.2
      Conserved Domains (2) summary
      pfam04652
      Location:22152
      Vta1; Vta1 like
      pfam18097
      Location:239276
      Vta1_C; Vta1 C-terminal domain
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