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    Myo19 myosin XIX [ Mus musculus (house mouse) ]

    Gene ID: 66196, updated on 18-Sep-2018

    Summary

    Official Symbol
    Myo19provided by MGI
    Official Full Name
    myosin XIXprovided by MGI
    Primary source
    MGI:MGI:1913446
    See related
    Ensembl:ENSMUSG00000020527 Vega:OTTMUSG00000001021
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Myohd1; 1110055A02Rik
    Expression
    Ubiquitous expression in colon adult (RPKM 17.9), kidney adult (RPKM 12.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Myo19 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (84880192..84911131)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (84693722..84724633)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930502E09 gene Neighboring gene gametogenetin binding protein 2 Neighboring gene gametogenetin binding protein 2, opposite strand Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class W Neighboring gene zinc finger, HIT type 3 Neighboring gene predicted gene, 33028 Neighboring gene predicted gene, 32917

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    myosin light chain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    plus-end directed microfilament motor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    mitochondrion migration along actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitochondrial fission ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    myosin complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    unconventional myosin-XIX
    Names
    myosin head domain containing 1
    myosin head domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362893.1NP_001349822.1  unconventional myosin-XIX isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK080117, AL645623
      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    2. NM_025414.4NP_079690.2  unconventional myosin-XIX isoform 1

      See identical proteins and their annotated locations for NP_079690.2

      Status: VALIDATED

      Source sequence(s)
      AK018609, AK080117, AL645623, BC060115, BU613548, CA749671
      Consensus CDS
      CCDS48871.1
      UniProtKB/Swiss-Prot
      Q5SV80
      Related
      ENSMUSP00000091502.4, OTTMUSP00000000977, ENSMUST00000093969.10
      Conserved Domains (3) summary
      smart00242
      Location:38754
      MYSc; Myosin. Large ATPases
      cd14880
      Location:49746
      MYSc_Myo19; class XIX myosin, motor domain
      pfam00612
      Location:784804
      IQ; IQ calmodulin-binding motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      84880192..84911131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249173.2XP_011247475.1  unconventional myosin-XIX isoform X1

      See identical proteins and their annotated locations for XP_011247475.1

      UniProtKB/Swiss-Prot
      Q5SV80
      Conserved Domains (3) summary
      smart00242
      Location:38754
      MYSc; Myosin. Large ATPases
      cd14880
      Location:49746
      MYSc_Myo19; class XIX myosin, motor domain
      pfam00612
      Location:784804
      IQ; IQ calmodulin-binding motif
    2. XM_011249175.2XP_011247477.1  unconventional myosin-XIX isoform X5

      See identical proteins and their annotated locations for XP_011247477.1

      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    3. XM_011249174.2XP_011247476.1  unconventional myosin-XIX isoform X2

      Conserved Domains (3) summary
      smart00242
      Location:38696
      MYSc; Myosin. Large ATPases
      cl22853
      Location:49688
      Motor_domain; Myosin and Kinesin motor domain
      pfam00612
      Location:726746
      IQ; IQ calmodulin-binding motif
    4. XM_006533929.3XP_006533992.1  unconventional myosin-XIX isoform X5

      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    5. XM_006533927.3XP_006533990.1  unconventional myosin-XIX isoform X4

      Conserved Domains (2) summary
      smart00242
      Location:38672
      MYSc; Myosin. Large ATPases
      cd14880
      Location:49699
      MYSc_Myo19; class XIX myosin, motor domain
    6. XM_017314704.1XP_017170193.1  unconventional myosin-XIX isoform X7

    7. XM_006533926.3XP_006533989.1  unconventional myosin-XIX isoform X3

      Conserved Domains (2) summary
      cl22853
      Location:1537
      Motor_domain; Myosin and Kinesin motor domain
      pfam00612
      Location:575595
      IQ; IQ calmodulin-binding motif
    8. XM_006533930.3XP_006533993.1  unconventional myosin-XIX isoform X6

      Conserved Domains (2) summary
      cl22853
      Location:1403
      Motor_domain; Myosin and Kinesin motor domain
      pfam00612
      Location:441461
      IQ; IQ calmodulin-binding motif

    RNA

    1. XR_879727.2 RNA Sequence

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