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    Myo19 myosin XIX [ Mus musculus (house mouse) ]

    Gene ID: 66196, updated on 8-Jul-2021

    Summary

    Official Symbol
    Myo19provided by MGI
    Official Full Name
    myosin XIXprovided by MGI
    Primary source
    MGI:MGI:1913446
    See related
    Ensembl:ENSMUSG00000020527
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Myohd; Myohd1; 1110055A02Rik
    Expression
    Ubiquitous expression in colon adult (RPKM 17.9), kidney adult (RPKM 12.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Myo19 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (84770996..84802052)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (84880170..84911226)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (84693722..84724633)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930502E09 gene Neighboring gene gametogenetin binding protein 2 Neighboring gene gametogenetin binding protein 2, opposite strand Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class W Neighboring gene zinc finger, HIT type 3 Neighboring gene predicted gene, 33028 Neighboring gene predicted gene, 32917 Neighboring gene carbonic anhydrase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables microfilament motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables myosin light chain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables plus-end directed microfilament motor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mitochondrion migration along actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrial fission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle transport along actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    unconventional myosin-XIX
    Names
    myosin head domain containing 1
    myosin head domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362893.1NP_001349822.1  unconventional myosin-XIX isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK080117, AL645623
      Related
      ENSMUST00000124152.8
      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    2. NM_025414.4NP_079690.2  unconventional myosin-XIX isoform 1

      See identical proteins and their annotated locations for NP_079690.2

      Status: VALIDATED

      Source sequence(s)
      AK018609, AK080117, AL645623, BC060115, BU613548, CA749671
      Consensus CDS
      CCDS48871.1
      UniProtKB/Swiss-Prot
      Q5SV80
      Related
      ENSMUSP00000091502.5, ENSMUST00000093969.11
      Conserved Domains (2) summary
      cd14880
      Location:49746
      MYSc_Myo19; class XIX myosin, motor domain
      pfam00612
      Location:784804
      IQ; IQ calmodulin-binding motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      84770996..84802052
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249173.3XP_011247475.1  unconventional myosin-XIX isoform X1

      See identical proteins and their annotated locations for XP_011247475.1

      UniProtKB/Swiss-Prot
      Q5SV80
      Conserved Domains (2) summary
      cd14880
      Location:49746
      MYSc_Myo19; class XIX myosin, motor domain
      pfam00612
      Location:784804
      IQ; IQ calmodulin-binding motif
    2. XM_036156894.1XP_036012787.1  unconventional myosin-XIX isoform X5

      Related
      ENSMUST00000141173.2
      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    3. XM_011249174.3XP_011247476.1  unconventional myosin-XIX isoform X2

      Conserved Domains (2) summary
      cl22853
      Location:49688
      Motor_domain; Myosin and Kinesin motor domain
      pfam00612
      Location:726746
      IQ; IQ calmodulin-binding motif
    4. XM_030246221.1XP_030102081.1  unconventional myosin-XIX isoform X4

      Conserved Domains (2) summary
      pfam00612
      Location:575595
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:1537
      Motor_domain; Myosin and Kinesin motor domain
    5. XM_036156892.1XP_036012785.1  unconventional myosin-XIX isoform X3

      Conserved Domains (2) summary
      pfam00612
      Location:639659
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:1601
      Motor_domain; Myosin and Kinesin motor domain
    6. XM_036156893.1XP_036012786.1  unconventional myosin-XIX isoform X4

      Conserved Domains (2) summary
      pfam00612
      Location:575595
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:1537
      Motor_domain; Myosin and Kinesin motor domain
    7. XM_036156895.1XP_036012788.1  unconventional myosin-XIX isoform X5

      Conserved Domains (2) summary
      pfam00612
      Location:511531
      IQ; IQ calmodulin-binding motif
      cl22853
      Location:18473
      Motor_domain; Myosin and Kinesin motor domain
    8. XM_006533930.4XP_006533993.1  unconventional myosin-XIX isoform X6

      Conserved Domains (2) summary
      cl22853
      Location:1403
      Motor_domain; Myosin and Kinesin motor domain
      pfam00612
      Location:441461
      IQ; IQ calmodulin-binding motif

    RNA

    1. XR_003949489.1 RNA Sequence

    2. XR_004937003.1 RNA Sequence

    3. XR_879727.4 RNA Sequence

    4. XR_004937004.1 RNA Sequence

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