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    Virma vir like m6A methyltransferase associated [ Mus musculus (house mouse) ]

    Gene ID: 66185, updated on 31-Jan-2019

    Summary

    Official Symbol
    Virmaprovided by MGI
    Official Full Name
    vir like m6A methyltransferase associatedprovided by MGI
    Primary source
    MGI:MGI:1913435
    See related
    Ensembl:ENSMUSG00000040720
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kiaa1429; mKIAA1429; 1110037F02Rik; 4930422M05Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 9.4), CNS E11.5 (RPKM 9.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Virma in Genome Data Viewer
    Location:
    4; 4 A1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (11485949..11551143)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (11413105..11478290)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35631 Neighboring gene predicted gene 11821 Neighboring gene predicted gene, 35693 Neighboring gene RAD54 homolog B (S. cerevisiae) Neighboring gene fibrinogen silencer binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA alternative polyadenylation ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA methylation ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    RNA N6-methyladenosine methyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA N6-methyladenosine methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with RNA N6-methyladenosine methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081183.1NP_001074652.1  protein virilizer homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL732538, AL772170
      Consensus CDS
      CCDS38693.1
      UniProtKB/TrEMBL
      E9PZY8
      Related
      ENSMUSP00000103943.2, ENSMUST00000108307.2
      Conserved Domains (2) summary
      pfam15502
      Location:17521857
      MPLKIP; M-phase-specific PLK1-interacting protein
      pfam15912
      Location:5236
      VIR_N; Virilizer, N-terminal
    2. NM_001347055.1NP_001333984.1  protein virilizer homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AL732538, AL772170
      Consensus CDS
      CCDS84705.1
      UniProtKB/Swiss-Prot
      A2AIV2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      11485949..11551143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538160.3XP_006538223.1  protein virilizer homolog isoform X1

      Related
      ENSMUSP00000058078.6, ENSMUST00000059914.12
      Conserved Domains (2) summary
      pfam15502
      Location:17021807
      MPLKIP; M-phase-specific PLK1-interacting protein
      pfam15912
      Location:5236
      VIR_N; Virilizer, N-terminal
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