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    Tmem14c transmembrane protein 14C [ Mus musculus (house mouse) ]

    Gene ID: 66154, updated on 18-Sep-2024

    Summary

    Official Symbol
    Tmem14cprovided by MGI
    Official Full Name
    transmembrane protein 14Cprovided by MGI
    Primary source
    MGI:MGI:1913404
    See related
    Ensembl:ENSMUSG00000021361 AllianceGenome:MGI:1913404
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HSPC194; 1110021D01Rik
    Summary
    Predicted to enable identical protein binding activity. Acts upstream of or within erythrocyte differentiation; mitochondrial transport; and regulation of heme biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; salivary gland; sensory organ; skeletal muscle; and thymus primordium. Orthologous to several human genes including TMEM14C (transmembrane protein 14C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 150.0), liver E14.5 (RPKM 146.6) and 27 other tissues See more
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    Genomic context

    See Tmem14c in Genome Data Viewer
    Location:
    13 A3.3; 13 20.25 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (41169726..41176058)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (41016250..41022582)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene glucosaminyl (N-acetyl) transferase 2 (I blood group) Neighboring gene predicted gene, 31683 Neighboring gene STARR-seq mESC enhancer starr_34294 Neighboring gene RIKEN cDNA A730081D07 gene Neighboring gene STARR-positive B cell enhancer ABC_E11542 Neighboring gene STARR-positive B cell enhancer ABC_E9874 Neighboring gene PAK1 interacting protein 1 Neighboring gene male germ cell-associated kinase Neighboring gene glial cells missing homolog 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360770.1NP_001347699.1  transmembrane protein 14C isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC133496
      UniProtKB/TrEMBL
      Q8C297
      Conserved Domains (1) summary
      pfam03647
      Location:594
      Tmemb_14; Transmembrane proteins 14C
    2. NM_025387.3NP_079663.1  transmembrane protein 14C isoform 1

      See identical proteins and their annotated locations for NP_079663.1

      Status: VALIDATED

      Source sequence(s)
      AK010609, BY785978, CO039120
      Consensus CDS
      CCDS26470.1
      UniProtKB/Swiss-Prot
      Q543H6, Q9CQN6, Q9D849
      Related
      ENSMUSP00000021790.6, ENSMUST00000021790.7
      Conserved Domains (1) summary
      pfam03647
      Location:13102
      Tmemb_14; Transmembrane proteins 14C

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      41169726..41176058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516938.3XP_006517001.1  transmembrane protein 14C isoform X1

      See identical proteins and their annotated locations for XP_006517001.1

      UniProtKB/TrEMBL
      Q8C297
      Conserved Domains (1) summary
      pfam03647
      Location:594
      Tmemb_14; Transmembrane proteins 14C