Format

Send to:

Choose Destination
    • Showing Current items.

    Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [ Mus musculus (house mouse) ]

    Gene ID: 66094, updated on 4-Jul-2021

    Summary

    Official Symbol
    Lsm7provided by MGI
    Official Full Name
    LSM7 homolog, U6 small nuclear RNA and mRNA degradation associatedprovided by MGI
    Primary source
    MGI:MGI:1913344
    See related
    Ensembl:ENSMUSG00000035215
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0910001B06Rik; 1110033F18Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 88.2), liver E14 (RPKM 73.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lsm7 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80688659..80691043, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80852825..80855209, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80315570..80317954, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene microRNA 1982 Neighboring gene ornithine decarboxylase antizyme 1 Neighboring gene leucine rich repeat and Ig domain containing 3 Neighboring gene signal peptide peptidase like 2B Neighboring gene transmembrane protease, serine 9 Neighboring gene translocase of inner mitochondrial membrane 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Lsm1-7-Pat1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Lsm2-8 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U6 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    U6 snRNA-associated Sm-like protein LSm7
    Names
    LSM7 homolog, U6 small nuclear RNA associated

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359148.1NP_001346077.1  U6 snRNA-associated Sm-like protein LSm7 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC166937, AK013355, BC027511
      Conserved Domains (1) summary
      cd01729
      Location:1098
      LSm7; Like-Sm protein 7
    2. NM_001359149.1NP_001346078.1  U6 snRNA-associated Sm-like protein LSm7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC166937, AK013355, BC027511
      Conserved Domains (1) summary
      cd01729
      Location:20108
      LSm7; Like-Sm protein 7
    3. NM_001359150.1NP_001346079.1  U6 snRNA-associated Sm-like protein LSm7 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC166937, AK013355, BC027511
      Related
      ENSMUST00000220406.2
      Conserved Domains (1) summary
      cd01729
      Location:21107
      LSm7; Like-Sm protein 7
    4. NM_025349.2NP_079625.1  U6 snRNA-associated Sm-like protein LSm7 isoform 4

      See identical proteins and their annotated locations for NP_079625.1

      Status: VALIDATED

      Source sequence(s)
      AK013355, BC027511
      Consensus CDS
      CCDS35987.1
      UniProtKB/Swiss-Prot
      Q9CQQ8
      Related
      ENSMUSP00000044993.9, ENSMUST00000035775.9
      Conserved Domains (1) summary
      cd01729
      Location:997
      LSm7; Like-Sm protein 7

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      80688659..80691043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center