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    Ghitm growth hormone inducible transmembrane protein [ Mus musculus (house mouse) ]

    Gene ID: 66092, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ghitmprovided by MGI
    Official Full Name
    growth hormone inducible transmembrane proteinprovided by MGI
    Primary source
    MGI:MGI:1913342
    See related
    Ensembl:ENSMUSG00000041028
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MICS1; PTD01; Tmbim; C77840; PTD010; Tmbim5; 1010001P14Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 84.7), kidney adult (RPKM 74.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ghitm in Genome Data Viewer
    Location:
    14 B; 14 21.29 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (36842401..36857279, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (37120444..37135322, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (37934004..37948452, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene cadherin-related family member 1 Neighboring gene RIKEN cDNA 2610528A11 gene Neighboring gene predicted gene, 18834 Neighboring gene predicted gene, 22469

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in inner mitochondrial membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    growth hormone-inducible transmembrane protein
    Names
    mitochondrial morphology and cristae structure 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199122.1NP_001186051.1  growth hormone-inducible transmembrane protein

      See identical proteins and their annotated locations for NP_001186051.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK149244, AK168678
      Consensus CDS
      CCDS26953.1
      UniProtKB/Swiss-Prot
      Q91VC9
      Related
      ENSMUSP00000046212.10, ENSMUST00000042564.17
      Conserved Domains (1) summary
      cd10431
      Location:82345
      GHITM; Growth-hormone inducible transmembrane protein
    2. NM_001359902.1NP_001346831.1  growth hormone-inducible transmembrane protein

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK149244, AK158904, CN530092, CO043730
      Consensus CDS
      CCDS26953.1
      Conserved Domains (1) summary
      cd10431
      Location:82345
      GHITM; Growth-hormone inducible transmembrane protein
    3. NM_078478.5NP_510963.1  growth hormone-inducible transmembrane protein

      See identical proteins and their annotated locations for NP_510963.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK149244, AK158904, BY141813
      Consensus CDS
      CCDS26953.1
      UniProtKB/Swiss-Prot
      Q91VC9
      Related
      ENSMUSP00000129712.3, ENSMUST00000165649.4
      Conserved Domains (1) summary
      cd10431
      Location:82345
      GHITM; Growth-hormone inducible transmembrane protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      36842401..36857279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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