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    Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 66075, updated on 23-Jun-2021

    Summary

    Official Symbol
    Chchd3provided by MGI
    Official Full Name
    coiled-coil-helix-coiled-coil-helix domain containing 3provided by MGI
    Primary source
    MGI:MGI:1913325
    See related
    Ensembl:ENSMUSG00000053768
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mico; Micos19; AW558177; 0610041L09Rik; 1700039J09Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 56.0), duodenum adult (RPKM 32.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Chchd3 in Genome Data Viewer
    Location:
    6; 6 A3.3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (32769142..33037206, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (32792207..33060273, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (32742227..33010152, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46956 Neighboring gene predicted gene, 32007 Neighboring gene predicted gene, 53279 Neighboring gene predicted gene, 22321 Neighboring gene zinc finger protein 212 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cristae formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner mitochondrial membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in inner mitochondrial membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial fusion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of MICOS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of MICOS complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    MICOS complex subunit Mic19
    Names
    coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355667.1NP_001342596.1  MICOS complex subunit Mic19

      Status: VALIDATED

      Source sequence(s)
      AC152943, AC156288
      Related
      ENSMUSP00000123220.2, ENSMUST00000127666.8
      Conserved Domains (1) summary
      pfam05300
      Location:15180
      DUF737; Protein of unknown function (DUF737)
    2. NM_025336.2NP_079612.1  MICOS complex subunit Mic19

      See identical proteins and their annotated locations for NP_079612.1

      Status: VALIDATED

      Source sequence(s)
      AC152943, AC156288
      Consensus CDS
      CCDS19986.1
      UniProtKB/Swiss-Prot
      Q9CRB9
      Related
      ENSMUSP00000070149.5, ENSMUST00000066379.11
      Conserved Domains (1) summary
      pfam05300
      Location:15175
      DUF737; Protein of unknown function (DUF737)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      32769142..33037206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152261.1XP_036008154.1  MICOS complex subunit Mic19 isoform X2

      Related
      ENSMUSP00000110743.2, ENSMUST00000115091.2
      Conserved Domains (1) summary
      pfam05300
      Location:20151
      DUF737; Protein of unknown function (DUF737)
    2. XM_006506468.5XP_006506531.1  MICOS complex subunit Mic19 isoform X1

      Conserved Domains (1) summary
      pfam05300
      Location:15156
      DUF737; Protein of unknown function (DUF737)
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