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    Ranbp17 RAN binding protein 17 [ Mus musculus (house mouse) ]

    Gene ID: 66011, updated on 12-Apr-2023

    Summary

    Official Symbol
    Ranbp17provided by MGI
    Official Full Name
    RAN binding protein 17provided by MGI
    Primary source
    MGI:MGI:1929706
    See related
    Ensembl:ENSMUSG00000040594 AllianceGenome:MGI:1929706
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to act upstream of or within nucleocytoplasmic transport. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. Orthologous to human RANBP17 (RAN binding protein 17). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 5.0), CNS E11.5 (RPKM 1.1) and 11 other tissues See more
    Orthologs
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    Genomic context

    See Ranbp17 in Genome Data Viewer
    Location:
    11; 11 A4
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2023_04 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (33161794..33463789, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (33211794..33513784, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12115 Neighboring gene T cell leukemia, homeobox 3 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene acidic (leucine-rich) nuclear phosphoprotein 32 family, pseudogene Neighboring gene mediator complex subunit 29 pseudogene Neighboring gene high mobility group box 2 pseudogene Neighboring gene CRISPRi-validated Ranbp17 enhancer cluster Neighboring gene predicted gene, 36005 Neighboring gene gamma-aminobutyric acid (GABA) A receptor, pi

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Clone Names

    • 4932704E15Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nuclear export signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables small GTPase binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nucleocytoplasmic transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in protein export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362875.1NP_001349804.1  ran-binding protein 17 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL669814, AL683843, AL772409
      Conserved Domains (2) summary
      smart00913
      Location:3095
      IBN_N; Importin-beta N-terminal domain
      cl26694
      Location:8167
      Xpo1; Exportin 1-like protein
    2. NM_023146.3NP_075635.1  ran-binding protein 17 isoform 1

      See identical proteins and their annotated locations for NP_075635.1

      Status: VALIDATED

      Source sequence(s)
      AK016583, AL669814, AL683843, AL772409, BY731762
      Consensus CDS
      CCDS24534.1
      UniProtKB/Swiss-Prot
      Q99NF8, Q9D4E3
      Related
      ENSMUSP00000099879.4, ENSMUST00000102815.10
      Conserved Domains (1) summary
      pfam03810
      Location:3095
      IBN_N; Importin-beta N-terminal domain

    RNA

    1. NR_110973.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK035897, AK050150, AL669814, AL772409, BY731762, CB527189

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      33161794..33463789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514776.5XP_006514839.1  ran-binding protein 17 isoform X1

      Conserved Domains (2) summary
      smart00913
      Location:3095
      IBN_N; Importin-beta N-terminal domain
      COG5101
      Location:8167
      CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]
    2. XM_011243739.4XP_011242041.1  ran-binding protein 17 isoform X2

      Conserved Domains (2) summary
      smart00913
      Location:3095
      IBN_N; Importin-beta N-terminal domain
      COG5101
      Location:8167
      CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]

    RNA

    1. XR_380976.5 RNA Sequence

    2. XR_380979.5 RNA Sequence

    3. XR_380977.5 RNA Sequence

    4. XR_003949487.2 RNA Sequence