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    Mrps23 mitochondrial ribosomal protein S23 [ Mus musculus (house mouse) ]

    Gene ID: 64656, updated on 31-Jan-2019

    Summary

    Official Symbol
    Mrps23provided by MGI
    Official Full Name
    mitochondrial ribosomal protein S23provided by MGI
    Primary source
    MGI:MGI:1928138
    See related
    Ensembl:ENSMUSG00000023723
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S23mt; Rpms23; MRP-S23; D11Bwg1153e
    Expression
    Ubiquitous expression in heart adult (RPKM 29.9), CNS E14 (RPKM 18.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Mrps23 in Genome Data Viewer
    Location:
    11 C; 11 52.4 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (88194106..88211507)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (88017920..88025009)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene vascular endothelial zinc finger 1 Neighboring gene RIKEN cDNA 2210416O15 gene Neighboring gene CUE domain containing 1 Neighboring gene predicted gene, 38534 Neighboring gene predicted gene, 34366

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • 2310047I09Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    intermediate filament cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    mitochondrion HDA PubMed 
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    28S ribosomal protein S23, mitochondrial
    Names
    mrps23

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291270.1NP_001278199.1  28S ribosomal protein S23, mitochondrial isoform b

      See identical proteins and their annotated locations for NP_001278199.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate 5-terminal exon, lacks part of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, and 4 encode the same isoform.
      Source sequence(s)
      AK014375, AL593853, AW121224
      Consensus CDS
      CCDS70279.1
      UniProtKB/Swiss-Prot
      Q8VE22
      UniProtKB/TrEMBL
      Q3TI14
      Conserved Domains (1) summary
      pfam10484
      Location:1109
      MRP-S23; Mitochondrial ribosomal protein S23
    2. NM_001291271.1NP_001278200.1  28S ribosomal protein S23, mitochondrial isoform b

      See identical proteins and their annotated locations for NP_001278200.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in the 5'-terminal exon, and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, and 4 encode the same isoform.
      Source sequence(s)
      AK014375, AL593853, AW121224, BY238199, BY794322
      Consensus CDS
      CCDS70279.1
      UniProtKB/Swiss-Prot
      Q8VE22
      UniProtKB/TrEMBL
      Q3TI14
      Conserved Domains (1) summary
      pfam10484
      Location:1109
      MRP-S23; Mitochondrial ribosomal protein S23
    3. NM_001291272.1NP_001278201.1  28S ribosomal protein S23, mitochondrial isoform b

      See identical proteins and their annotated locations for NP_001278201.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate splice site in the 5'-terminal exon, and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, and 4 encode the same isoform.
      Source sequence(s)
      AK014375, AW121224, BY238199, BY794322
      Consensus CDS
      CCDS70279.1
      UniProtKB/Swiss-Prot
      Q8VE22
      UniProtKB/TrEMBL
      Q3TI14
      Related
      ENSMUSP00000113512.1, ENSMUST00000118784.7
      Conserved Domains (1) summary
      pfam10484
      Location:1109
      MRP-S23; Mitochondrial ribosomal protein S23
    4. NM_001291273.1NP_001278202.1  28S ribosomal protein S23, mitochondrial isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an exon in the central coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.
      Source sequence(s)
      AK014375, AW121224, BY238199
      UniProtKB/Swiss-Prot
      Q8VE22
      Related
      ENSMUSP00000122963.1, ENSMUST00000144070.2
      Conserved Domains (1) summary
      cl24037
      Location:271
      MRP-S23; Mitochondrial ribosomal protein S23
    5. NM_024174.6NP_077136.2  28S ribosomal protein S23, mitochondrial isoform a

      See identical proteins and their annotated locations for NP_077136.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AK014375, AW121224, BY238199
      Consensus CDS
      CCDS25227.1
      UniProtKB/Swiss-Prot
      Q8VE22
      Related
      ENSMUSP00000024486.7, ENSMUST00000024486.13
      Conserved Domains (1) summary
      pfam10484
      Location:2128
      MRP-S23; Mitochondrial ribosomal protein S23

    RNA

    1. NR_111902.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) uses an alternate splice site in the 5'-terminal exon, and lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK014375, AW121224, BY238199, BY794322

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      88194106..88211507
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 PATCHES

    Genomic

    1. NW_004450260.1 Reference GRCm38.p4 PATCHES

      Range
      199530..216931
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_187003.1 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      1330278..1347907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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