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    Dhx38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [ Mus musculus (house mouse) ]

    Gene ID: 64340, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dhx38provided by MGI
    Official Full Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 38provided by MGI
    Primary source
    MGI:MGI:1927617
    See related
    Ensembl:ENSMUSG00000037993
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ddx38; Prp16; AI325984; AW540902; KIAA0224; 5730550P09Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 12.7), CNS E11.5 (RPKM 11.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dhx38 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (109548003..109565856, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (112071924..112089501, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene polyamine modulated factor 1 binding protein 1 Neighboring gene predicted gene, 35145 Neighboring gene predicted gene, 39246 Neighboring gene thioredoxin-like 4B Neighboring gene haptoglobin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP-dependent 3'-5' RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
    Names
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38
    pre-mRNA splicing factor 16
    NP_848467.1
    XP_006531324.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178380.2NP_848467.1  pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

      See identical proteins and their annotated locations for NP_848467.1

      Status: VALIDATED

      Source sequence(s)
      AC125162, AI503007, BC046557
      Consensus CDS
      CCDS22652.1
      UniProtKB/TrEMBL
      Q80X98
      Related
      ENSMUSP00000047865.7, ENSMUST00000042601.8
      Conserved Domains (5) summary
      smart00490
      Location:759862
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:527714
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:9311013
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:552688
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:10641147
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RNA

    1. NR_151644.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC125162

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      109548003..109565856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531261.2XP_006531324.1  pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 isoform X1

      Conserved Domains (5) summary
      smart00490
      Location:758861
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:526713
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:9301012
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:551687
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:10631146
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RNA

    1. XR_387769.2 RNA Sequence

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