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    Nrbf2 nuclear receptor binding factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 641340, updated on 24-Aug-2021

    Summary

    Official Symbol
    Nrbf2provided by MGI
    Official Full Name
    nuclear receptor binding factor 2provided by MGI
    Primary source
    MGI:MGI:1354950
    See related
    Ensembl:ENSMUSG00000075000
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NRBF-2
    Expression
    Ubiquitous expression in adrenal adult (RPKM 8.0), bladder adult (RPKM 6.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nrbf2 in Genome Data Viewer
    Location:
    10; 10 B5.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (67102468..67121128, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (67266689..67285343, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (66729437..66748029, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31763 Neighboring gene receptor accessory protein 3 Neighboring gene jumonji domain containing 1C Neighboring gene predicted gene, 26359 Neighboring gene predicted gene, 46200 Neighboring gene predicted gene, 46229

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in autophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of lipid kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in response to endoplasmic reticulum stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of phosphatidylinositol 3-kinase complex, class III IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    nuclear receptor-binding factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001036293.2NP_001031370.1  nuclear receptor-binding factor 2

      See identical proteins and their annotated locations for NP_001031370.1

      Status: PROVISIONAL

      Source sequence(s)
      AC155712
      Consensus CDS
      CCDS23902.1
      UniProtKB/Swiss-Prot
      Q8VCQ3
      Related
      ENSMUSP00000097254.4, ENSMUST00000077839.13
      Conserved Domains (1) summary
      pfam08961
      Location:46284
      DUF1875; Domain of unknown function (DUF1875)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      67102468..67121128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314049.3XP_017169538.1  nuclear receptor-binding factor 2 isoform X2

      Conserved Domains (2) summary
      pfam17169
      Location:142
      NRBF2_MIT; MIT domain of nuclear receptor-binding factor 2
      pfam08961
      Location:45240
      NRBF2; Nuclear receptor-binding factor 2, autophagy regulator
    2. XM_036155939.1XP_036011832.1  nuclear receptor-binding factor 2 isoform X1

      Conserved Domains (2) summary
      pfam08961
      Location:118313
      NRBF2; Nuclear receptor-binding factor 2, autophagy regulator
      pfam17169
      Location:39115
      NRBF2_MIT; MIT domain of nuclear receptor-binding factor 2
    3. XM_006513938.4XP_006514001.1  nuclear receptor-binding factor 2 isoform X3

      Conserved Domains (2) summary
      pfam17169
      Location:2875
      NRBF2_MIT; MIT domain of nuclear receptor-binding factor 2
      pfam08961
      Location:78273
      NRBF2; Nuclear receptor-binding factor 2, autophagy regulator
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