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    Gmfb glia maturation factor, beta [ Mus musculus (house mouse) ]

    Gene ID: 63985, updated on 5-Sep-2021

    Summary

    Official Symbol
    Gmfbprovided by MGI
    Official Full Name
    glia maturation factor, betaprovided by MGI
    Primary source
    MGI:MGI:1927133
    See related
    Ensembl:ENSMUSG00000062014
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C79176; AI851627; D14Ertd630; D14Ertd630e; 3110001H22Rik; 3110001O16Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 25.4), frontal lobe adult (RPKM 21.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gmfb in Genome Data Viewer
    Location:
    14 C1; 14 24.32 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (47045606..47059711, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (46808149..46822259, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (47427824..47441917, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene cyclin-dependent kinase inhibitor 3 Neighboring gene cornichon family AMPA receptor auxiliary protein 1 Neighboring gene cell growth regulator with ring finger domain 1 Neighboring gene predicted gene, 34934

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables Arp2/3 complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in actin filament debranching IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within learning IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    glia maturation factor beta
    Names
    GMF-beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022023.2NP_071306.2  glia maturation factor beta

      See identical proteins and their annotated locations for NP_071306.2

      Status: VALIDATED

      Source sequence(s)
      AC093043
      Consensus CDS
      CCDS36898.1
      UniProtKB/Swiss-Prot
      Q9CQI3
      Related
      ENSMUSP00000107448.2, ENSMUST00000111817.8
      Conserved Domains (1) summary
      cd11283
      Location:9130
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      47045606..47059711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247909.2XP_030103769.1  glia maturation factor beta isoform X1

      Conserved Domains (1) summary
      cd11283
      Location:9131
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
    2. XM_030247913.1XP_030103773.1  glia maturation factor beta isoform X3

      Conserved Domains (1) summary
      cd11283
      Location:197
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
    3. XM_036158778.1XP_036014671.1  glia maturation factor beta isoform X3

      Conserved Domains (1) summary
      cd11283
      Location:197
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
    4. XM_030247912.1XP_030103772.1  glia maturation factor beta isoform X3

      Conserved Domains (1) summary
      cd11283
      Location:197
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
    5. XM_030247911.1XP_030103771.1  glia maturation factor beta isoform X3

      Conserved Domains (1) summary
      cd11283
      Location:197
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
    6. XM_030247910.1XP_030103770.1  glia maturation factor beta isoform X2

      Conserved Domains (1) summary
      cd11283
      Location:198
      ADF_GMF-beta_like; ADF-homology domain of glia maturation factor beta and related proteins
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