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    Zfp977 zinc finger protein 977 [ Mus musculus (house mouse) ]

    Gene ID: 637776, updated on 4-Feb-2026
    Official Symbol
    Zfp977provided by MGI
    Official Full Name
    zinc finger protein 977provided by MGI
    Primary source
    MGI:MGI:3645327
    See related
    Ensembl:ENSMUSG00000092335 AllianceGenome:MGI:3645327
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm7221; EG637776
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Orthologous to human ZNF670 (zinc finger protein 670). [provided by Alliance of Genome Resources, Jul 2025]
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    See Zfp977 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (42228821..42241969, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (42579397..42592545, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4921 Neighboring gene predicted gene, 35353 Neighboring gene STARR-seq mESC enhancer starr_18740 Neighboring gene STARR-seq mESC enhancer starr_18741 Neighboring gene predicted gene, 53386 Neighboring gene STARR-seq mESC enhancer starr_18742 Neighboring gene STARR-seq mESC enhancer starr_18744 Neighboring gene predicted gene, 21028 Neighboring gene zinc finger protein 976 Neighboring gene STARR-seq mESC enhancer starr_18745 Neighboring gene zinc finger protein 975 Neighboring gene STARR-seq mESC enhancer starr_18747

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    zinc finger protein 977

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362112.1 → NP_001349041.1  zinc finger protein 977

      Status: VALIDATED

      Source sequence(s)
      AC102606, CD538311, CJ078437
      Consensus CDS
      CCDS90215.1
      UniProtKB/TrEMBL
      L7N2E7
      Related
      ENSMUSP00000134517.2, ENSMUST00000173283.3
      Conserved Domains (5) summary
      COG5048
      Location:185 → 369
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:351 → 430
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:357 → 377
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
      pfam13465
      Location:145 → 168
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      42228821..42241969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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