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    Sap30 sin3 associated polypeptide [ Mus musculus (house mouse) ]

    Gene ID: 60406, updated on 2-Oct-2018

    Summary

    Official Symbol
    Sap30provided by MGI
    Official Full Name
    sin3 associated polypeptideprovided by MGI
    Primary source
    MGI:MGI:1929129
    See related
    Ensembl:ENSMUSG00000031609 Vega:OTTMUSG00000029898
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    30kDa
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 34.9), CNS E14 (RPKM 18.2) and 26 other tissues See more
    Orthologs

    Genomic context

    See Sap30 in Genome Data Viewer
    Location:
    8 B2; 8 29.85 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (57482702..57487860, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (59961499..59966657, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene mannosidase 2, alpha 2 pseudogene Neighboring gene scrapie responsive gene 1 Neighboring gene RIKEN cDNA 2500002B13 gene Neighboring gene high mobility group box 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    histone deacetylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Sin3 complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    histone deacetylase complex subunit SAP30
    Names
    30 kDa Sin3-associated polypeptide
    Sin3-associated protein
    sap30
    sin3 associated polypeptide, 30kD
    sin3 corepressor complex subunit SAP30
    sin3-associated polypeptide p30
    sin3-associated polypeptide, 30 kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021788.2NP_068560.1  histone deacetylase complex subunit SAP30

      See identical proteins and their annotated locations for NP_068560.1

      Status: VALIDATED

      Source sequence(s)
      AK010928, AV144112, BC132081, CO800093
      Consensus CDS
      CCDS22316.1
      UniProtKB/Swiss-Prot
      O88574
      Related
      ENSMUSP00000034022.3, OTTMUSP00000038507, ENSMUST00000034022.3, OTTMUST00000074177
      Conserved Domains (2) summary
      pfam13866
      Location:65133
      zf-SAP30; SAP30 zinc-finger
      pfam13867
      Location:154202
      SAP30_Sin3_bdg; Sin3 binding region of histone deacetylase complex subunit SAP30

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      57482702..57487860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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