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    Cope coatomer protein complex, subunit epsilon [ Mus musculus (house mouse) ]

    Gene ID: 59042, updated on 19-Mar-2019

    Summary

    Official Symbol
    Copeprovided by MGI
    Official Full Name
    coatomer protein complex, subunit epsilonprovided by MGI
    Primary source
    MGI:MGI:1891702
    See related
    Ensembl:ENSMUSG00000055681
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cope1; 1110005D17Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 240.8), ovary adult (RPKM 233.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cope in Genome Data Viewer
    Location:
    8; 8 B3.3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (70302785..70312990)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (72826684..72836889)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 38427 Neighboring gene homer scaffolding protein 3 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 Neighboring gene ceramide synthase 1 Neighboring gene growth differentiation factor 1 Neighboring gene UPF1 regulator of nonsense transcripts homolog (yeast) Neighboring gene cartilage oligomeric matrix protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    ER to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    retrograde vesicle-mediated transport, Golgi to ER IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    COPI-coated vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coatomer subunit epsilon
    Names
    epsilon-COP
    epsilon-coat protein
    nonclathrin coat protein epsilon-COP

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021538.2NP_067513.1  coatomer subunit epsilon

      See identical proteins and their annotated locations for NP_067513.1

      Status: VALIDATED

      Source sequence(s)
      AC158553
      Consensus CDS
      CCDS22365.1
      UniProtKB/Swiss-Prot
      O89079
      Related
      ENSMUSP00000071078.7, ENSMUST00000066469.13
      Conserved Domains (2) summary
      pfam04733
      Location:17305
      Coatomer_E; Coatomer epsilon subunit
      sd00006
      Location:185210
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      70302785..70312990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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