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    Rhot1 ras homolog family member T1 [ Mus musculus (house mouse) ]

    Gene ID: 59040, updated on 17-Aug-2021

    Summary

    Official Symbol
    Rhot1provided by MGI
    Official Full Name
    ras homolog family member T1provided by MGI
    Primary source
    MGI:MGI:1926078
    See related
    Ensembl:ENSMUSG00000017686
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mi; Arh; Arht1; Miro1; AA415293; AF244542; AI834919; 2210403N23Rik; C430039G08Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 10.8), bladder adult (RPKM 10.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rhot1 in Genome Data Viewer
    Location:
    11 B5; 11 47.62 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (80099844..80158733)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (80208610..80267907)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (80022557..80081409)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ArfGAP with dual PH domains 2 Neighboring gene ring finger protein 135 Neighboring gene rhomboid like 3 Neighboring gene RIKEN cDNA 5730455P16 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ11040

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial outer membrane permeabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrion transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrion transport along microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    mitochondrial Rho GTPase 1
    Names
    ras homolog gene family, member T1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163354.2NP_001156826.1  mitochondrial Rho GTPase 1 isoform 2

      See identical proteins and their annotated locations for NP_001156826.1

      Status: VALIDATED

      Source sequence(s)
      AK147801, AL591426
      Consensus CDS
      CCDS48861.1
      UniProtKB/Swiss-Prot
      Q8BG51
      Related
      ENSMUSP00000017831.9, ENSMUST00000017831.16
      Conserved Domains (5) summary
      smart00174
      Location:20182
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01892
      Location:428593
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354422
      EF_assoc_1; EF hand associated
      pfam08356
      Location:234314
      EF_assoc_2; EF hand associated
    2. NM_001163355.2NP_001156827.1  mitochondrial Rho GTPase 1 isoform 3

      See identical proteins and their annotated locations for NP_001156827.1

      Status: VALIDATED

      Source sequence(s)
      AK147801, AK167502, AL591426
      Consensus CDS
      CCDS48862.1
      UniProtKB/Swiss-Prot
      Q8BG51
      Related
      ENSMUSP00000057669.10, ENSMUST00000055056.16
      Conserved Domains (5) summary
      smart00174
      Location:20182
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01892
      Location:428594
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354422
      EF_assoc_1; EF hand associated
      pfam08356
      Location:234314
      EF_assoc_2; EF hand associated
    3. NM_001362868.1NP_001349797.1  mitochondrial Rho GTPase 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL591426
      Consensus CDS
      CCDS88206.1
      Related
      ENSMUSP00000076664.8, ENSMUST00000077451.14
      Conserved Domains (4) summary
      cd01892
      Location:428593
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354422
      EF_assoc_1; EF hand associated
      pfam08356
      Location:232316
      EF_assoc_2; EF hand associated
    4. NM_001362869.1NP_001349798.1  mitochondrial Rho GTPase 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL591426
      Conserved Domains (4) summary
      cd01892
      Location:341506
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      pfam08355
      Location:267335
      EF_assoc_1; EF hand associated
      pfam08356
      Location:145229
      EF_assoc_2; EF hand associated
      cl21455
      Location:3695
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    5. NM_001362870.1NP_001349799.1  mitochondrial Rho GTPase 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL591426
      Related
      ENSMUSP00000117941.2, ENSMUST00000134894.2
      Conserved Domains (4) summary
      cd01892
      Location:288454
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      pfam08355
      Location:214282
      EF_assoc_1; EF hand associated
      pfam08356
      Location:92176
      EF_assoc_2; EF hand associated
      cl21455
      Location:142
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    6. NM_021536.8NP_067511.4  mitochondrial Rho GTPase 1 isoform 1

      See identical proteins and their annotated locations for NP_067511.4

      Status: VALIDATED

      Source sequence(s)
      AK054472, AK147801, AL591426
      Consensus CDS
      CCDS25130.1
      UniProtKB/Swiss-Prot
      Q8BG51
      Related
      ENSMUSP00000090533.7, ENSMUST00000092857.13
      Conserved Domains (5) summary
      smart00174
      Location:20182
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01892
      Location:428605
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354422
      EF_assoc_1; EF hand associated
      pfam08356
      Location:234314
      EF_assoc_2; EF hand associated

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      80099844..80158733
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533886.5XP_006533949.1  mitochondrial Rho GTPase 1 isoform X1

      Conserved Domains (4) summary
      cd01892
      Location:428593
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354423
      EF_assoc_1; EF hand associated
      pfam08356
      Location:232316
      EF_assoc_2; EF hand associated
    2. XM_011249167.4XP_011247469.1  mitochondrial Rho GTPase 1 isoform X2

      Conserved Domains (4) summary
      cd01892
      Location:428594
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:16182
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:354423
      EF_assoc_1; EF hand associated
      pfam08356
      Location:232316
      EF_assoc_2; EF hand associated

    RNA

    1. XR_879726.4 RNA Sequence

    2. XR_003949484.2 RNA Sequence

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