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    Edf1 endothelial differentiation-related factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 59022, updated on 31-Jan-2019

    Summary

    Official Symbol
    Edf1provided by MGI
    Official Full Name
    endothelial differentiation-related factor 1provided by MGI
    Primary source
    MGI:MGI:1891227
    See related
    Ensembl:ENSMUSG00000015092
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MBF1; AA409425; 0610008L11Rik
    Expression
    Ubiquitous expression in small intestine adult (RPKM 103.6), duodenum adult (RPKM 81.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Edf1 in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (25557821..25562082)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25413420..25417602)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene TNF receptor-associated factor 2 Neighboring gene cytochrome c oxidase subunit 7A2, mitochondrial pseudogene Neighboring gene predicted gene, 35476 Neighboring gene MAM domain containing 4 Neighboring gene phosphohistidine phosphatase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    TFIID-class transcription factor complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    endothelial differentiation-related factor 1
    Names
    hypothetical protein 1-9
    multiprotein-bridging factor 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021519.2NP_067494.1  endothelial differentiation-related factor 1

      See identical proteins and their annotated locations for NP_067494.1

      Status: VALIDATED

      Source sequence(s)
      AB030185, BB856073, CF740336
      Consensus CDS
      CCDS15780.1
      UniProtKB/Swiss-Prot
      Q9JMG1
      Related
      ENSMUSP00000015236.3, ENSMUST00000015236.3
      Conserved Domains (2) summary
      pfam08523
      Location:472
      MBF1; Multiprotein bridging factor 1
      cl26727
      Location:48142
      aMBF1; Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      25557821..25562082
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498208.2XP_006498271.1  endothelial differentiation-related factor 1 isoform X1

      Conserved Domains (1) summary
      pfam08523
      Location:47115
      MBF1; Multiprotein bridging factor 1
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