Format

Send to:

Choose Destination
    • Showing Current items.

    Erg28 ergosterol biosynthesis 28 [ Mus musculus (house mouse) ]

    Gene ID: 58520, updated on 31-Jan-2019

    Summary

    Official Symbol
    Erg28provided by MGI
    Official Full Name
    ergosterol biosynthesis 28provided by MGI
    Primary source
    MGI:MGI:1915571
    See related
    Ensembl:ENSMUSG00000021252
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ORF11; C77855; AU019315; 0610007P14Rik; 1190004E09Rik
    Expression
    Ubiquitous expression in liver adult (RPKM 36.5), placenta adult (RPKM 33.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Erg28 in Genome Data Viewer
    Location:
    12; 12 D2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (85815447..85824920, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (87156405..87165495, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene basic leucine zipper transcription factor, ATF-like Neighboring gene feline leukemia virus subgroup C cellular receptor 2 Neighboring gene predicted gene, 40478 Neighboring gene tubulin tyrosine ligase-like family, member 5 Neighboring gene transforming growth factor, beta 3 Neighboring gene intraflagellar transport 43

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • 0610007P14Rik, 1190004E09Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding, bridging IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    ergosterol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    probable ergosterol biosynthetic protein 28
    Names
    c14orf1-like protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360451.1NP_001347380.1  probable ergosterol biosynthetic protein 28 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice acceptor site in the 5' UTR region, compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AC138303, AI844820, DV047491
      Conserved Domains (1) summary
      pfam03694
      Location:8115
      Erg28; Erg28 like protein
    2. NM_001360813.1NP_001347742.1  probable ergosterol biosynthetic protein 28 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC138303, AI851047, BE656456
      Conserved Domains (1) summary
      pfam03694
      Location:875
      Erg28; Erg28 like protein
    3. NM_021446.3NP_067421.1  probable ergosterol biosynthetic protein 28 isoform 1

      See identical proteins and their annotated locations for NP_067421.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AC138303, AI844820, AK004480
      Consensus CDS
      CCDS26063.1
      UniProtKB/Swiss-Prot
      Q9ERY9
      Related
      ENSMUSP00000021676.5, ENSMUST00000021676.11
      Conserved Domains (1) summary
      pfam03694
      Location:8115
      Erg28; Erg28 like protein

    RNA

    1. NR_153807.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice donor site, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC138303, AI844820, AK004480

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      85815447..85824920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516117.2XP_006516180.1  probable ergosterol biosynthetic protein 28 isoform X1

      UniProtKB/Swiss-Prot
      Q9ERY9
      Conserved Domains (1) summary
      pfam03694
      Location:8115
      Erg28; Erg28 like protein
    Support Center