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    Slc35b4 solute carrier family 35, member B4 [ Mus musculus (house mouse) ]

    Gene ID: 58246, updated on 18-Sep-2024

    Summary

    Official Symbol
    Slc35b4provided by MGI
    Official Full Name
    solute carrier family 35, member B4provided by MGI
    Primary source
    MGI:MGI:1931249
    See related
    Ensembl:ENSMUSG00000018999 AllianceGenome:MGI:1931249
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930474D06Rik
    Summary
    Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Acts upstream of or within regulation of gluconeogenesis. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SLC35B4 (solute carrier family 35 member B4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in kidney adult (RPKM 32.1), genital fat pad adult (RPKM 17.7) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc35b4 in Genome Data Viewer
    Location:
    6 A3.3; 6 14.75 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (34132810..34153921, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (34155872..34177054, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13853 Neighboring gene STARR-positive B cell enhancer ABC_E10372 Neighboring gene predicted gene, 38786 Neighboring gene leucine-rich repeats and guanylate kinase domain containing Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:34079401-34079510 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:34106119-34106374 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:34126896-34127097 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:34132037-34132238 Neighboring gene STARR-seq mESC enhancer starr_15530 Neighboring gene predicted gene 13855 Neighboring gene predicted gene, 32533 Neighboring gene STARR-seq mESC enhancer starr_15531

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleotide sugar transporter SLC35B4
    Names
    UDP-xylose and UDP-N-acetylglucosamine transporter

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021435.4NP_067410.1  nucleotide sugar transporter SLC35B4

      See identical proteins and their annotated locations for NP_067410.1

      Status: VALIDATED

      Source sequence(s)
      AC153817
      Consensus CDS
      CCDS19989.1
      UniProtKB/Swiss-Prot
      Q3TQU7, Q5U681, Q8CIA5, Q9JJF7
      Related
      ENSMUSP00000019143.9, ENSMUST00000019143.9
      Conserved Domains (2) summary
      pfam08449
      Location:2314
      UAA; UAA transporter family
      cl23754
      Location:87310
      EamA; EamA-like transporter family

    RNA

    1. NR_184551.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC153817

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      34132810..34153921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)