Format

Send to:

Choose Destination
    • Showing Current items.

    Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 [ Mus musculus (house mouse) ]

    Gene ID: 58233, updated on 16-Oct-2021

    Summary

    Official Symbol
    Dnaja4provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member A4provided by MGI
    Primary source
    MGI:MGI:1927638
    See related
    Ensembl:ENSMUSG00000032285
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dj4; Hsj4; mmDjA4; AV358213; 1110021L12Rik
    Expression
    Broad expression in testis adult (RPKM 35.2), heart adult (RPKM 15.3) and 20 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dnaja4 in Genome Data Viewer
    Location:
    9; 9 A5.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54606132..54623601)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54698848..54716317)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (54547366..54564119)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene 5730494N06Rik pseudogene Neighboring gene predicted gene, 46113 Neighboring gene microRNA 5710 Neighboring gene WD repeat domain 61 Neighboring gene cellular retinoic acid binding protein I

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables unfolded protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of inclusion body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein refolding ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to heat IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily A member 4
    Names
    DnaJ (Hsp40) homolog, subfamily A, member 4
    heat shock protein, DNAJ-like 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357875.1NP_001344804.1  dnaJ homolog subfamily A member 4 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC159892, AK141909, KY499677
      Conserved Domains (1) summary
      cl28246
      Location:15423
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    2. NM_021422.4NP_067397.1  dnaJ homolog subfamily A member 4 isoform 2

      See identical proteins and their annotated locations for NP_067397.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC159892, AK076175
      Consensus CDS
      CCDS23193.1
      UniProtKB/Swiss-Prot
      Q9JMC3
      Related
      ENSMUSP00000070413.8, ENSMUST00000070070.8
      Conserved Domains (4) summary
      cd10719
      Location:135201
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:106332
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
      PTZ00037
      Location:2394
      PTZ00037; DnaJ_C chaperone protein; Provisional
      pfam00226
      Location:765
      DnaJ; DnaJ domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      54606132..54623601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004935508.1 RNA Sequence

    2. XR_001778951.2 RNA Sequence

    Support Center