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    Spata5 spermatogenesis associated 5 [ Mus musculus (house mouse) ]

    Gene ID: 57815, updated on 23-Jun-2021

    Summary

    Official Symbol
    Spata5provided by MGI
    Official Full Name
    spermatogenesis associated 5provided by MGI
    Primary source
    MGI:MGI:1927170
    See related
    Ensembl:ENSMUSG00000027722
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; Spaf; C78064; 2510048F20Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 3.8), placenta adult (RPKM 3.4) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Spata5 in Genome Data Viewer
    Location:
    3; 3 B
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (37474052..37633245)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (37419903..37579096)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (37319202..37478017)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 12 (human) Neighboring gene 28S ribosomal protein S33, mitochondrial pseudogene Neighboring gene fibroblast growth factor 2, opposite strand Neighboring gene fibroblast growth factor 2 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 6 Neighboring gene predicted gene, 36412 Neighboring gene RIKEN cDNA 4930594O21 gene Neighboring gene PRELI domain containing 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in brain development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ATPase family protein 2 homolog
    Names
    spermatogenesis-associated factor protein
    spermatogenesis-associated protein 5
    NP_001156983.1
    NP_001297402.1
    NP_067318.2
    XP_017175162.1
    XP_030108596.1
    XP_036019090.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163511.2NP_001156983.1  ATPase family protein 2 homolog isoform 1

      See identical proteins and their annotated locations for NP_001156983.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK011111, AL669927, BY106106, CO043526
      Consensus CDS
      CCDS50895.1
      UniProtKB/Swiss-Prot
      Q3UMC0
      Related
      ENSMUSP00000103747.4, ENSMUST00000108112.10
      Conserved Domains (3) summary
      COG0464
      Location:370882
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:664796
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21693
      Location:64132
      CDC48_N; Cell division protein 48 (CDC48), N-terminal domain
    2. NM_001310473.1NP_001297402.1  ATPase family protein 2 homolog isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate internal exon, resulting in a frameshift and an early stop codon compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK011111, AL669927, BY106106, CO043526, DN175568
      Consensus CDS
      CCDS79900.1
      UniProtKB/Swiss-Prot
      Q3UMC0
      UniProtKB/TrEMBL
      A0A0G2JFY0
      Related
      ENSMUSP00000143349.2, ENSMUST00000198968.2
      Conserved Domains (3) summary
      COG0464
      Location:370835
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:664796
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21693
      Location:64132
      CDC48_N; Cell division protein 48 (CDC48), N-terminal domain
    3. NM_021343.3NP_067318.2  ATPase family protein 2 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.
      Source sequence(s)
      AK011111, AL669927, BY106106, CO043526
      Consensus CDS
      CCDS17321.1
      UniProtKB/Swiss-Prot
      Q3UMC0
      UniProtKB/TrEMBL
      A0A0A0MQ80
      Related
      ENSMUSP00000029277.9, ENSMUST00000029277.13
      Conserved Domains (3) summary
      COG0464
      Location:369881
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:663795
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21693
      Location:63131
      CDC48_N; Cell division protein 48 (CDC48), N-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      37474052..37633245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252736.1XP_030108596.1  ATPase family protein 2 homolog isoform X2

      Conserved Domains (2) summary
      TIGR01243
      Location:322834
      CDC48; AAA family ATPase, CDC48 subfamily
      cl21693
      Location:63131
      CDC48_N; Cell division protein 48 (CDC48), N-terminal domain
    2. XM_036163197.1XP_036019090.1  ATPase family protein 2 homolog isoform X1

      Conserved Domains (2) summary
      TIGR01243
      Location:323835
      CDC48; AAA family ATPase, CDC48 subfamily
      cl21693
      Location:64132
      CDC48_N; Cell division protein 48 (CDC48), N-terminal domain
    3. XM_017319673.1XP_017175162.1  ATPase family protein 2 homolog isoform X3

      Conserved Domains (1) summary
      TIGR01243
      Location:1466
      CDC48; AAA family ATPase, CDC48 subfamily
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