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    Bin3 bridging integrator 3 [ Mus musculus (house mouse) ]

    Gene ID: 57784, updated on 5-Sep-2021

    Summary

    Official Symbol
    Bin3provided by MGI
    Official Full Name
    bridging integrator 3provided by MGI
    Primary source
    MGI:MGI:1929883
    See related
    Ensembl:ENSMUSG00000022089
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700015F07Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 5.9), liver E14 (RPKM 5.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Bin3 in Genome Data Viewer
    Location:
    14; 14 D2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (70337538..70375413)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (70100089..70137964)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (70499952..70538013)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene phosphatidylethanolamine binding protein 4 Neighboring gene predicted gene, 33524 Neighboring gene early growth response 3 Neighboring gene RIKEN cDNA 9930012K11 gene Neighboring gene cell cycle activator and apoptosis regulator 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360404.1NP_001347333.1  bridging integrator 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC151836, AI464318, AK005992, BB682940, CA562064, CX565660
      Conserved Domains (1) summary
      cl12013
      Location:1192
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    2. NM_021328.4NP_067303.1  bridging integrator 3 isoform 1

      See identical proteins and their annotated locations for NP_067303.1

      Status: VALIDATED

      Source sequence(s)
      AC151836, AI464318, AK005992, BB682940, CA562064
      Consensus CDS
      CCDS27247.1
      UniProtKB/Swiss-Prot
      Q9JI08
      Related
      ENSMUSP00000022680.8, ENSMUST00000022680.9
      Conserved Domains (1) summary
      cd07590
      Location:12236
      BAR_Bin3; The Bin/Amphiphysin/Rvs (BAR) domain of Bridging integrator 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      70337538..70375413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519330.4XP_006519393.1  bridging integrator 3 isoform X1

      Conserved Domains (1) summary
      cd07590
      Location:12209
      BAR_Bin3; The Bin/Amphiphysin/Rvs (BAR) domain of Bridging integrator 3
    2. XM_030247901.1XP_030103761.1  bridging integrator 3 isoform X3

      Conserved Domains (1) summary
      cl12013
      Location:1114
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    3. XM_006519332.4XP_006519395.1  bridging integrator 3 isoform X2

      See identical proteins and their annotated locations for XP_006519395.1

      Conserved Domains (1) summary
      cl12013
      Location:1192
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    4. XM_030247902.1XP_030103762.1  bridging integrator 3 isoform X3

      Conserved Domains (1) summary
      cl12013
      Location:1114
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    5. XM_036158770.1XP_036014663.1  bridging integrator 3 isoform X2

      Conserved Domains (1) summary
      cl12013
      Location:1192
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    6. XM_036158771.1XP_036014664.1  bridging integrator 3 isoform X2

      Conserved Domains (1) summary
      cl12013
      Location:1192
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    7. XM_011245124.2XP_011243426.1  bridging integrator 3 isoform X3

      Conserved Domains (1) summary
      cl12013
      Location:1114
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
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