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    Noc3l NOC3 like DNA replication regulator [ Mus musculus (house mouse) ]

    Gene ID: 57753, updated on 23-Jun-2021

    Summary

    Official Symbol
    Noc3lprovided by MGI
    Official Full Name
    NOC3 like DNA replication regulatorprovided by MGI
    Primary source
    MGI:MGI:1932610
    See related
    Ensembl:ENSMUSG00000024999
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fad2; Fad24; AF233884
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 6.0), limb E14.5 (RPKM 4.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Noc3l in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (38776565..38808754, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (38788121..38820310, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (38862618..38893727, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46666 Neighboring gene phospholipase C, epsilon 1 Neighboring gene adaptor protein complex AP-2, mu1 pseudogene Neighboring gene TBC1D12: TBC1 domain family, member 12 Neighboring gene helicase, lymphoid specific

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleolar complex protein 3 homolog
    Names
    NOC3 protein homolog
    NOC3-like protein
    factor for adipocyte differentiation 24
    nucleolar complex associated 3 homolog
    nucleolar complex-associated protein 3-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021315.2NP_067290.2  nucleolar complex protein 3 homolog

      See identical proteins and their annotated locations for NP_067290.2

      Status: VALIDATED

      Source sequence(s)
      AC101775, AC111023, AC158131
      Consensus CDS
      CCDS37974.1
      UniProtKB/Swiss-Prot
      Q8VI84
      Related
      ENSMUSP00000025963.8, ENSMUST00000025963.8
      Conserved Domains (3) summary
      COG5117
      Location:113712
      NOC3; Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion]
      pfam03914
      Location:554707
      CBF; CBF/Mak21 family
      pfam07540
      Location:213307
      NOC3p; Nucleolar complex-associated protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      38776565..38808754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_386499.4 RNA Sequence

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