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    ZNF492 zinc finger protein 492 [ Homo sapiens (human) ]

    Gene ID: 57615, updated on 23-Nov-2023

    Summary

    Official Symbol
    ZNF492provided by HGNC
    Official Full Name
    zinc finger protein 492provided by HGNC
    Primary source
    HGNC:HGNC:23707
    See related
    Ensembl:ENSG00000229676 MIM:620124; AllianceGenome:HGNC:23707
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZNF115
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis (RPKM 1.4), bone marrow (RPKM 0.9) and 16 other tissues See more
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    Genomic context

    Location:
    19p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (22634324..22667671)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (22772936..22806289)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (22817126..22850473)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RAD54L2 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1785 Neighboring gene zinc finger protein 849, pseudogene Neighboring gene ribosomal protein L34 pseudogene 33

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1473, MGC129633, MGC148019

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 492
    Names
    zinc finger protein 115 (Y20)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020855.3NP_065906.1  zinc finger protein 492

      See identical proteins and their annotated locations for NP_065906.1

      Status: VALIDATED

      Source sequence(s)
      AB040906, AC011467, BP871882
      Consensus CDS
      CCDS46032.1
      UniProtKB/Swiss-Prot
      Q08EI7, Q08EI8, Q9P255
      Related
      ENSP00000413660.2, ENST00000456783.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      22634324..22667671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047439130.1XP_047295086.1  zinc finger protein 492 isoform X1

      UniProtKB/Swiss-Prot
      Q08EI7, Q08EI8, Q9P255
    2. XM_047439131.1XP_047295087.1  zinc finger protein 492 isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      22772936..22806289
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054321544.1XP_054177519.1  zinc finger protein 492 isoform X1

      UniProtKB/Swiss-Prot
      Q08EI7, Q08EI8, Q9P255
    2. XM_054321545.1XP_054177520.1  zinc finger protein 492 isoform X2