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    Gmnn geminin [ Mus musculus (house mouse) ]

    Gene ID: 57441, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gmnnprovided by MGI
    Official Full Name
    gemininprovided by MGI
    Primary source
    MGI:MGI:1927344
    See related
    Ensembl:ENSMUSG00000006715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gem; AW546347
    Expression
    Biased expression in liver E14 (RPKM 43.4), CNS E11.5 (RPKM 31.4) and 12 other tissues See more
    Orthologs

    Genomic context

    See Gmnn in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (24751845..24761937, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (24843714..24853806, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene RHO family interacting cell polarization regulator 2 Neighboring gene X-linked lymphocyte-regulated 5 pseudogene Neighboring gene armadillo-like helical domain containing 2 Neighboring gene cDNA sequence BC005537 Neighboring gene acyl-CoA thioesterase 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone deacetylase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    repressing transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    animal organ morphogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of DNA replication IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020567.2NP_065592.1  geminin

      See identical proteins and their annotated locations for NP_065592.1

      Status: VALIDATED

      Source sequence(s)
      AK131959, BY045588, CF751770
      Consensus CDS
      CCDS26378.1
      UniProtKB/Swiss-Prot
      O88513
      UniProtKB/TrEMBL
      Q3V295
      Related
      ENSMUSP00000106011.2, ENSMUST00000110382.8
      Conserved Domains (1) summary
      pfam07412
      Location:1186
      Geminin; Geminin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      24751845..24761937 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516723.3XP_006516786.1  geminin isoform X1

      See identical proteins and their annotated locations for XP_006516786.1

      UniProtKB/Swiss-Prot
      O88513
      UniProtKB/TrEMBL
      Q3V295
      Related
      ENSMUSP00000135823.1, ENSMUST00000175689.7
      Conserved Domains (1) summary
      pfam07412
      Location:1186
      Geminin; Geminin
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