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    Zc3h8 zinc finger CCCH type containing 8 [ Mus musculus (house mouse) ]

    Gene ID: 57432, updated on 2-Oct-2018

    Summary

    Official Symbol
    Zc3h8provided by MGI
    Official Full Name
    zinc finger CCCH type containing 8provided by MGI
    Primary source
    MGI:MGI:1930128
    See related
    Ensembl:ENSMUSG00000027387 Vega:OTTMUSG00000015426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fliz1; Zc3hdc8; AU020882; E130108N08Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 4.3), CNS E18 (RPKM 4.1) and 24 other tissues See more
    Orthologs

    Genomic context

    See Zc3h8 in Genome Data Viewer
    Location:
    2; 2 F1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (128926268..128944084, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (128752004..128769756, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene fibulin 7 Neighboring gene predicted gene, 46763 Neighboring gene predicted gene 14028 Neighboring gene zinc finger CCCH type containing 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    T cell homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of T cell differentiation in thymus ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of thymocyte apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase III ISO
    Inferred from Sequence Orthology
    more info
     
    response to antibiotic ISO
    Inferred from Sequence Orthology
    more info
     
    snRNA transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    snRNA transcription by RNA polymerase III ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Cajal body ISO
    Inferred from Sequence Orthology
    more info
     
    histone locus body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription elongation factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptionally active chromatin ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger CCCH domain-containing protein 8
    Names
    fetal liver zinc finger 1
    fetal liver zinc finger 1; putative zinc finger protein FLIZ1
    fetal liver zinc finger protein 1
    zinc finger CCCH type domain containing 8

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020594.2NP_065619.2  zinc finger CCCH domain-containing protein 8

      See identical proteins and their annotated locations for NP_065619.2

      Status: VALIDATED

      Source sequence(s)
      BC048687, CJ167668
      Consensus CDS
      CCDS16718.1
      UniProtKB/Swiss-Prot
      Q9JJ48
      Related
      ENSMUSP00000028866.8, OTTMUSP00000016437, ENSMUST00000028866.8, OTTMUST00000036629
      Conserved Domains (1) summary
      smart00356
      Location:240260
      ZnF_C3H1; zinc finger

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      128926268..128944084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499947.2XP_006500010.1  zinc finger CCCH domain-containing protein 8 isoform X1

      Conserved Domains (1) summary
      smart00356
      Location:236256
      ZnF_C3H1; zinc finger
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