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    Brd4 bromodomain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 57261, updated on 26-Oct-2021

    Summary

    Official Symbol
    Brd4provided by MGI
    Official Full Name
    bromodomain containing 4provided by MGI
    Primary source
    MGI:MGI:1888520
    See related
    Ensembl:ENSMUSG00000024002
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Brd5; MCAP; HUNK1; WI-11513
    Summary
    This gene was temporarily named bromodomain-containing 5 (Brd5) and was renamed bromodomain-containing 4 (Brd4). [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in thymus adult (RPKM 17.8), spleen adult (RPKM 13.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Brd4 in Genome Data Viewer
    Location:
    17 B1; 17 17.39 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (32415246..32503717, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32196272..32284743, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (32333219..32421068, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1733 Neighboring gene epoxide hydrolase 3 Neighboring gene predicted gene 4432 Neighboring gene A kinase (PRKA) anchor protein 8 Neighboring gene A kinase (PRKA) anchor protein 8-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTP-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables P-TEFb complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II C-terminal domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables RNA polymerase II C-terminal domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lysine-acetylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables p53 binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coregulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within histone H3-K14 acetylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within histone H4-K12 acetylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within inner cell mass cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation by host of viral transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA damage checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of G2/M transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of histone H3-K36 trimethylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of transcription elongation from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within protein phosphorylation IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    involved_in regulation of inflammatory response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of phosphorylation of RNA polymerase II C-terminal domain ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of transcription involved in G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in condensed nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cyclin/CDK positive transcription elongation factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    bromodomain-containing protein 4
    Names
    bromodomain-containing 5
    fsh-like protein
    mitotic chromosome-associated protein
    NP_001273559.1
    NP_065254.3
    NP_932762.2
    XP_006524746.1
    XP_006524747.1
    XP_006524748.1
    XP_006524749.1
    XP_006524751.1
    XP_006524752.1
    XP_006524754.1
    XP_006524756.1
    XP_017173077.1
    XP_030105784.1
    XP_030105785.1
    XP_030105786.1
    XP_030105787.1
    XP_030105790.1
    XP_030105791.1
    XP_030105792.1
    XP_036016585.1
    XP_036016586.1
    XP_036016587.1
    XP_036016588.1
    XP_036016589.1
    XP_036016590.1
    XP_036016591.1
    XP_036016592.1
    XP_036016593.1
    XP_036016594.1
    XP_036016595.1
    XP_036016596.1
    XP_036016597.1
    XP_036016598.1
    XP_036016599.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286630.1NP_001273559.1  bromodomain-containing protein 4 isoform 3

      See identical proteins and their annotated locations for NP_001273559.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longest isoform (3).
      Source sequence(s)
      AK147545, BY779550, CJ192204
      Consensus CDS
      CCDS70784.1
      UniProtKB/TrEMBL
      Q3UH70
      Related
      ENSMUSP00000003726.9, ENSMUST00000003726.16
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    2. NM_020508.4NP_065254.3  bromodomain-containing protein 4 isoform 1

      See identical proteins and their annotated locations for NP_065254.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) has two alternate splice sites, one in the 5' UTR and one in the 5' coding region, compared to variant 3. The resulting isoform (1) lacks an internal aa, compared to isoform 3.
      Source sequence(s)
      AK147545, BY779550, CJ192204
      Consensus CDS
      CCDS50057.1
      UniProtKB/Swiss-Prot
      Q9ESU6
      UniProtKB/TrEMBL
      Q3UH70
      Related
      ENSMUSP00000113070.2, ENSMUST00000121285.8
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    3. NM_198094.2NP_932762.2  bromodomain-containing protein 4 isoform 2

      See identical proteins and their annotated locations for NP_932762.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has two alternate splice sites, one in the 5' UTR and one in the 5' coding region, and also lacks several exons but includes an alternate 3' terminal exon, compared to variant 3. The resulting isoform (2) lacks an internal aa, and has a shorter and distinct C-terminus, compared to isoform 3.
      Source sequence(s)
      AF461396, BC138834, BY779550
      Consensus CDS
      CCDS37554.1
      UniProtKB/Swiss-Prot
      Q9ESU6
      UniProtKB/TrEMBL
      B2RSE4
      Related
      ENSMUSP00000112474.3, ENSMUST00000120276.9
      Conserved Domains (3) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      32415246..32503717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524691.2XP_006524754.1  bromodomain-containing protein 4 isoform X4

      Conserved Domains (5) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7991212
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13251367
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    2. XM_006524688.3XP_006524751.1  bromodomain-containing protein 4 isoform X2

      See identical proteins and their annotated locations for XP_006524751.1

      UniProtKB/Swiss-Prot
      Q9ESU6
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    3. XM_006524689.4XP_006524752.1  bromodomain-containing protein 4 isoform X2

      See identical proteins and their annotated locations for XP_006524752.1

      UniProtKB/Swiss-Prot
      Q9ESU6
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    4. XM_006524683.4XP_006524746.1  bromodomain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006524746.1

      UniProtKB/TrEMBL
      Q3UH70
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    5. XM_030249930.2XP_030105790.1  bromodomain-containing protein 4 isoform X6

      Conserved Domains (4) summary
      cd05498
      Location:206307
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6441082
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:462526
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12101252
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    6. XM_036160698.1XP_036016591.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    7. XM_006524684.4XP_006524747.1  bromodomain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006524747.1

      UniProtKB/TrEMBL
      Q3UH70
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    8. XM_030249931.2XP_030105791.1  bromodomain-containing protein 4 isoform X6

      Conserved Domains (4) summary
      cd05498
      Location:206307
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6441082
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:462526
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12101252
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    9. XM_036160701.1XP_036016594.1  bromodomain-containing protein 4 isoform X5

      Conserved Domains (4) summary
      cd05498
      Location:207308
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6451083
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:463527
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12111253
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    10. XM_030249932.2XP_030105792.1  bromodomain-containing protein 4 isoform X6

      Conserved Domains (4) summary
      cd05498
      Location:206307
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6441082
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:462526
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12101252
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    11. XM_036160703.1XP_036016596.1  bromodomain-containing protein 4 isoform X6

      Conserved Domains (4) summary
      cd05498
      Location:206307
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6441082
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:462526
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12101252
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    12. XM_006524693.4XP_006524756.1  bromodomain-containing protein 4 isoform X6

      Conserved Domains (4) summary
      cd05498
      Location:206307
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6441082
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:462526
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12101252
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    13. XM_036160700.1XP_036016593.1  bromodomain-containing protein 4 isoform X5

      Conserved Domains (4) summary
      cd05498
      Location:207308
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6451083
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:463527
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12111253
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    14. XM_030249926.2XP_030105786.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    15. XM_030249925.2XP_030105785.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    16. XM_030249927.2XP_030105787.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    17. XM_006524686.3XP_006524749.1  bromodomain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006524749.1

      UniProtKB/TrEMBL
      Q3UH70
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    18. XM_006524685.3XP_006524748.1  bromodomain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006524748.1

      UniProtKB/TrEMBL
      Q3UH70
      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    19. XM_036160697.1XP_036016590.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    20. XM_036160693.1XP_036016586.1  bromodomain-containing protein 4 isoform X1

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    21. XM_036160696.1XP_036016589.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    22. XM_036160692.1XP_036016585.1  bromodomain-containing protein 4 isoform X1

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    23. XM_036160694.1XP_036016587.1  bromodomain-containing protein 4 isoform X1

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    24. XM_030249924.2XP_030105784.1  bromodomain-containing protein 4 isoform X2

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7921230
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12661307
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13581400
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    25. XM_036160699.1XP_036016592.1  bromodomain-containing protein 4 isoform X3

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:8001213
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12341275
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13261368
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    26. XM_017317588.3XP_017173077.1  bromodomain-containing protein 4 isoform X5

      Conserved Domains (4) summary
      cd05498
      Location:207308
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6451083
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:463527
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12111253
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    27. XM_036160695.1XP_036016588.1  bromodomain-containing protein 4 isoform X1

      Conserved Domains (6) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:7931231
      PHA03247; large tegument protein UL36; Provisional
      pfam13868
      Location:12671308
      TPH; Trichohyalin-plectin-homology domain
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:13591401
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    28. XM_036160702.1XP_036016595.1  bromodomain-containing protein 4 isoform X5

      Conserved Domains (4) summary
      cd05498
      Location:207308
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6451083
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:463527
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12111253
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    29. XM_036160704.1XP_036016597.1  bromodomain-containing protein 4 isoform X5

      Conserved Domains (4) summary
      cd05498
      Location:207308
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:6451083
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:463527
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:12111253
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    30. XM_036160706.1XP_036016599.1  bromodomain-containing protein 4 isoform X8

      Conserved Domains (3) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:354455
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:610674
      BET; Bromodomain extra-terminal - transcription regulation
    31. XM_036160705.1XP_036016598.1  bromodomain-containing protein 4 isoform X7

      Conserved Domains (3) summary
      cd05497
      Location:58164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:355456
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:611675
      BET; Bromodomain extra-terminal - transcription regulation
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