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    Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 [ Mus musculus (house mouse) ]

    Gene ID: 56752, updated on 3-Feb-2019

    Summary

    Official Symbol
    Aldh9a1provided by MGI
    Official Full Name
    aldehyde dehydrogenase 9, subfamily A1provided by MGI
    Primary source
    MGI:MGI:1861622
    See related
    Ensembl:ENSMUSG00000026687
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Abaldh; ESTM40; Tmabadh; AA139417; TMABA-DH
    Expression
    Ubiquitous expression in kidney adult (RPKM 54.7), liver adult (RPKM 50.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Aldh9a1 in Genome Data Viewer
    Location:
    1; 1 H2.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (167349991..167368530)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (169280122..169298661)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene microRNA 6347 Neighboring gene transmembrane and coiled-coil domains 1 Neighboring gene microsomal glutathione S-transferase 3 Neighboring gene predicted gene, 34207 Neighboring gene leucine rich repeat containing 52

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    4-trimethylammoniobutyraldehyde dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    4-trimethylammoniobutyraldehyde dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    NAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    aldehyde dehydrogenase (NAD) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    aldehyde dehydrogenase (NAD) activity ISO
    Inferred from Sequence Orthology
    more info
     
    amine binding ISO
    Inferred from Sequence Orthology
    more info
     
    aminobutyraldehyde dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    aminobutyraldehyde dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    carnitine metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular aldehyde metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    neurotransmitter biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    4-trimethylaminobutyraldehyde dehydrogenase
    Names
    aldehyde dehydrogenase family 9 member A1
    gamma-aminobutyraldehyde dehydrogenase
    NP_064377.2
    XP_006497013.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019993.4NP_064377.2  4-trimethylaminobutyraldehyde dehydrogenase precursor

      See identical proteins and their annotated locations for NP_064377.2

      Status: VALIDATED

      Source sequence(s)
      AC113970
      Consensus CDS
      CCDS35765.1
      UniProtKB/Swiss-Prot
      Q9JLJ2
      UniProtKB/TrEMBL
      Q3TMT4, Q3U367, Q3V1N7
      Related
      ENSMUSP00000028004.9, ENSMUST00000028004.10
      Conserved Domains (1) summary
      cd07090
      Location:55512
      ALDH_F9_TMBADH; NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      167349991..167368530
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496950.3XP_006497013.1  4-trimethylaminobutyraldehyde dehydrogenase isoform X1

      Conserved Domains (1) summary
      cl11961
      Location:1312
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily
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